Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 3/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3570210 | 0.90 | FFAR1 (0.46) | SLC2A1LPAR1LPAR5FFAR1FFAR4 | |
| SCHEMBL3575570 | 0.89 | TRPV1 (0.42) | SLC2A1LPAR1LMNALPAR5HPGD | |
| SCHEMBL3577779 | 0.88 | FFAR1 (0.43) | SLC2A1LPAR1LMNALPAR5HPGD | |
| SCHEMBL3576064 | 0.88 | LMNA (0.46) | SLC2A1LPAR1LMNALPAR5HPGD | |
| SCHEMBL3579168 | 0.88 | SLC2A1 (0.41) | SLC2A1LPAR1LMNALPAR5HPGD | |
| SCHEMBL3576819 | 0.88 | SLC2A1 (0.41) | SLC2A1LPAR1LMNALPAR5HPGD | |
| SCHEMBL3573413 | 0.87 | LMNA (0.44) | SLC2A1LPAR1LMNALPAR5HPGD | |
| SCHEMBL3584461 | 0.87 | LMNA (0.44) | SLC2A1LPAR1LMNALPAR5HPGD | |
| SCHEMBL3585679 | 0.87 | LMNA (0.44) | SLC2A1LPAR1LMNALPAR5HPGD | |
| SCHEMBL3576939 | 0.86 | SLC2A1 (0.41) | SLC2A1LPAR1LMNALPAR5HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |