Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.49 |
| ▸ | MAOB | P27338 | 6/20 | 0.43 |
| ▸ | MAOA | P21397 | 5/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3571519 | 0.78 | PPARG (0.49) | PPARGMAOBMAOAFFAR1 | |
| SCHEMBL3585202 | 0.78 | PPARG (0.49) | PPARGMAOBMAOAFFAR1 | |
| SCHEMBL3571521 | 0.78 | PPARG (0.49) | PPARGMAOBMAOAFFAR1 | |
| SCHEMBL3573231 | 0.76 | PPARG (0.48) | PPARGMAOBMAOA | |
| SCHEMBL3573234 | 0.76 | PPARG (0.48) | PPARGMAOBMAOA | |
| SCHEMBL3573229 | 0.76 | PPARG (0.48) | PPARGMAOBMAOA | |
| SCHEMBL13316126 | 0.73 | PPARG (0.62) | PPARGMAOBMAOA | |
| SCHEMBL27655240 | 0.72 | PPARG (0.60) | PPARGMAOBMAOAFFAR1 | |
| SCHEMBL3567986 | 0.72 | PPARG (0.60) | PPARGMAOBMAOAFFAR1 | |
| SCHEMBL3567958 | 0.70 | PPARG (0.63) | PPARGMAOBMAOAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7741323-B2 | Indene derivatives and process for the preparation thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2010-06-22 | — | — | US | claimed |
| US-20070185109-A1 | Idene derivatives and process for the preparation thereof | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2007-08-09 | — | — | US | claimed |
| US-7741323-B2 | Indene derivatives and process for the preparation thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2010-06-22 | — | — | US | disclosed |
| US-20070185109-A1 | Idene derivatives and process for the preparation thereof | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185109-A1 | Idene derivatives and process for the preparation thereof | INSR, PPARD, GPR119 | PPARG 5/4885MAOB 3350/4885MAOA 3544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.