SCHEMBL3581847

SCHEMBL3581847

NC(COCc1ccccc1)C(=O)NCCN1CCOCC1

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
HPGD P15428 1/20 0.50
CD274 Q9NZQ7 1/20 0.50
POLB P06746 1/20 0.49
TACR2 P21452 3/20 0.48
TACR3 P29371 1/20 0.48
LMNA P02545 1/20 0.48
CYP3A4 P08684 1/20 0.48
ALDH1A1 P00352 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7287023 0.84 MEN1 (0.60) MEN1KMT2AHPGDCD274POLB
SCHEMBL12310426 0.84 MEN1 (0.60) MEN1KMT2AHPGDCD274POLB
SCHEMBL7405696 0.82 TACR2 (0.62) KMT2ATACR2LMNAALDH1A1
SCHEMBL3586021 0.81 KMT2A (0.46) MEN1KMT2APOLBLMNAALDH1A1
SCHEMBL3586820 0.79 SLC1A1 (0.52) LMNA
SCHEMBL7653278 0.79 HSD17B10 (0.67) MEN1KMT2AHPGDCD274TACR3
SCHEMBL12310313 0.78 TACR3 (0.59) HPGDCD274TACR2TACR3LMNA
SCHEMBL6044214 0.78 MEN1 (0.57) MEN1KMT2AHPGDCD274POLB
SCHEMBL12260483 0.78 TACR3 (0.59) HPGDCD274TACR2TACR3LMNA
SCHEMBL30899745 0.77 MEN1 (0.58) MEN1KMT2AHPGDCD274POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100048549-A1 Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 Wurster, Siegfried (FI) 2010-02-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048549-A1 Peptidomimetics selective for the somatostatin receptor subtypes 1 and/or 4 SSTR1, SSTR4, SSTR3 MEN1 488/4885KMT2A 2996/4885HPGD 4277/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.