Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5524703 | 1.00 | MAPT (0.47) | MAPTKMT2ACYP2C19HIF1ACYP1A2 | |
| SCHEMBL6829887 | 0.77 | MAPT (0.50) | MAPTKMT2ACYP2C19HIF1ACYP1A2 | |
| SCHEMBL3726386 | 0.73 | CYP1A2 (0.54) | MAPTKMT2ACYP2C19HIF1ACYP1A2 | |
| Acetic Acid SCHEMBL11528737 | 0.73 | MAPT (0.50) | MAPTKMT2ACYP2C19HIF1ACYP1A2 | |
| Ethane SCHEMBL14127500 | 0.73 | CYP1A2 (0.48) | MAPTKMT2ACYP2C19HIF1ACYP1A2 | |
| SCHEMBL112992 | 0.72 | CYP1A2 (0.52) | MAPTKMT2ACYP2C19HIF1ACYP1A2 | |
| SCHEMBL31276141 | 0.72 | CYP1A2 (0.52) | MAPTKMT2ACYP2C19HIF1ACYP1A2 | |
| SCHEMBL4592372 | 0.72 | CYP1A2 (0.52) | MAPTKMT2ACYP2C19HIF1ACYP1A2 | |
| SCHEMBL1560417 | 0.72 | MAPT (0.54) | MAPTKMT2ACYP2C19HIF1ACYP1A2 | |
| SCHEMBL73063 | 0.72 | HDAC3 (0.61) | MAPTKMT2ACYP2C19HIF1ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11780935-B2 | Mutant antibodies and conjugation thereof | PFIZER HEALTHCARE IRELAND (IE) | 2023-10-10 | — | — | US | disclosed |
| CN-116333053-A | Atosiban and method for inhibiting formation of polymeric impurities | 海南中和药业股份有限公司 | 2023-06-27 | — | — | CN | disclosed |
| US-20220273664-A1 | Mitochondrial Targeted Releasable Linker | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2022-09-01 | — | — | US | disclosed |
| US-20210147576-A1 | MUTANT ANTIBODIES AND CONJUGATION THEREOF | PFIZER HEALTHCARE IRELAND (IE) | 2021-05-20 | — | — | US | disclosed |
| EP-3395358-B1 | INSULIN ANALOG DIMERS | UNIV INDIANA RES & TECH CORP (US) | 2019-11-06 | — | — | EP | disclosed |
| EP-2900255-B1 | INSULIN ANALOG DIMERS | UNIV INDIANA RES & TECH CORP (US) | 2019-01-30 | — | — | EP | disclosed |
| WO-2018232491-A1 | MITOCHONDRIAL TARGETED RELEASABLE LINKER | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2018-12-27 | — | — | WO | disclosed |
| EP-3395358-A1 | INSULIN ANALOG DIMERS | Indiana University Research and Technology Corporation (US) | 2018-10-31 | — | — | EP | disclosed |
| EP-2593142-B1 | MULTIFUNCTIONAL ANTIBODY CONJUGATES | COVX TECH IRELAND LIMITED (IE) | 2018-10-10 | — | — | EP | disclosed |
| EP-2802355-B1 | MUTANT ANTIBODIES AND CONJUGATION THEREOF | COVX TECH IRELAND LIMITED (IE) | 2018-09-05 | — | — | EP | disclosed |
| US-7869958-B2 | Structure-based modulators of B1 G-protein coupled receptors | RESEARCH DEVELOPMENT FOUNDATION (US) | 2011-01-11 | — | — | US | disclosed |
| EP-2164519-A2 | LONG-ACTING POLYMERIC PRODRUGS OF EXENDIN | Ascendis Pharma AS (DK) | 2010-03-24 | — | — | EP | disclosed |
| WO-2008148839-A2 | LONG-ACTING POLYMERIC PRODRUGS OF EXENDIN | ASCENDIS PHARMA AS (DK) | 2008-12-11 | — | — | WO | disclosed |
| US-7312195-B2 | Cyclised conotoxin peptides | THE UNIVERSITY OF QUEENSLAND (AU) | 2007-12-25 | — | — | US | disclosed |
| US-20060069516-A1 | Structure-based modulators of B1 G-protein coupled receptors | RESEARCH DEVELOPMENT FOUNDATION (US) | 2006-03-30 | — | — | US | disclosed |
| WO-2006031322-A2 | DETERMINATION OF THE 3D-STRUCTURE OF AN EXTRACELLULAR DOMAIN OF A B1 G-PROTEIN COUPLED RECEPTOR BY NMR ANALYSIS | RESEARCH DEVELOPMENT FOUNDATION (US) | 2006-03-23 | — | — | WO | disclosed |
| US-20050256301-A1 | Cyclised conotoxin peptides | THE UNIVERSITY OF QUEENSLAND (AU) | 2005-11-17 | — | — | US | disclosed |
| EP-0013261-B1 | GUAIACOL ESTERS OF ALPHA- AND BETA-MERCAPTOPROPIONYLALANINE AND ALPHA- AND BETA-MERCAPTOPROPIONYLGLYCINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1982-12-01 | — | — | EP | disclosed |
| US-4299842-A | TREATMENT OF RESPIRATORY SYSTEM DISORDERS, NUCOLYTIC AGENTS | CAVAZZA CLAUDIO | 1981-11-10 | — | — | US | disclosed |
| EP-0013261-A1 | Guaiacol esters of alpha- and beta-mercaptopropionylalanine and alpha- and beta-mercaptopropionylglycine, process for their preparation and pharmaceutical compositions containing same | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 1980-07-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210147576-A1 | MUTANT ANTIBODIES AND CONJUGATION THEREOF | IGLV6-57, IGSF11, F13B | MAPT 114/4885KMT2A 1718/4885CYP2C19 4260/4885 |
| US-20050256301-A1 | Cyclised conotoxin peptides | VIP, CANX, IAPP | MAPT 1962/4885KMT2A 4153/4885CYP2C19 2581/4885 |
| US-11780935-B2 | Mutant antibodies and conjugation thereof | IGLV6-57, IGSF11, F13B | MAPT 104/4885KMT2A 1715/4885CYP2C19 4254/4885 |
| US-20220273664-A1 | Mitochondrial Targeted Releasable Linker | PDF, NDUFAB1, AURKAIP1 | MAPT 1202/4885KMT2A 3845/4885CYP2C19 2837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.