⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3587837 | 1.00 | — | — | |
| SCHEMBL1959295 | 1.00 | — | — | |
| SCHEMBL12050694 | 0.82 | ALDH1A1 (0.58) | — | |
| SCHEMBL4596643 | 0.82 | ALDH1A1 (0.58) | — | |
| SCHEMBL14460704 | 0.82 | ALDH1A1 (0.58) | — | |
| SCHEMBL4102536 | 0.82 | ALDH1A1 (0.58) | — | |
| SCHEMBL14779933 | 0.80 | ALDH1A1 (0.55) | — | |
| SCHEMBL17801120 | 0.80 | ALDH1A1 (0.55) | — | |
| SCHEMBL5280109 | 0.80 | ALDH1A1 (0.55) | — | |
| SCHEMBL2756235 | 0.80 | ALDH1A1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12239630-B2 | Carboxylic acid aromatic amides as antagonists of bradykinin B1 receptor | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2025-03-04 | — | — | US | disclosed |
| CN-118324762-A | Compounds and compositions for treating CNS disorders | 布鲁奥科制药有限公司 | 2024-07-12 | — | — | CN | disclosed |
| US-12023319-B2 | Carboxylic acid aromatic amides | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2024-07-02 | — | — | US | disclosed |
| US-12023319-B2 | Carboxylic acid aromatic amides | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2024-07-02 | — | — | US | disclosed |
| US-11905270-B2 | Carboxylic acid aromatic amides as antagonists of bradykinin B1 receptor | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2024-02-20 | — | — | US | disclosed |
| CN-117062811-A | 3- (1-oxo-isoindolin-2-yl) piperidine-2, 6-dione derivatives and medical use thereof | 诺华股份有限公司 | 2023-11-14 | — | — | CN | disclosed |
| US-20230271931-A1 | CARBOXYLIC ACID AROMATIC AMIDES AS ANTAGONISTS OF BRADYKININ B1 RECEPTOR | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2023-08-31 | — | — | US | disclosed |
| US-20230271931-A1 | CARBOXYLIC ACID AROMATIC AMIDES AS ANTAGONISTS OF BRADYKININ B1 RECEPTOR | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2023-08-31 | — | — | US | disclosed |
| US-20230109801-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS | BLUE OAK PHARMACEUTICALS, INC. | 2023-04-13 | — | — | US | disclosed |
| US-20230116114-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CNS DISORDERS | BLUE OAK PHARMACEUTICALS, INC. | 2023-04-13 | — | — | US | disclosed |
| US-6677335-B1 | PYRAZOLO(4,3-D)PYRIMIDIN-7-ONE DERIVATIVES; CYCLIC GUANOSINE 3',5'-MONOPHOSPHATE PHOSPHODIESTERASE INHIBITORS; SEXUAL AND UROGENITAL DISORDERS | PFIZER INC | 2004-01-13 | — | — | US | disclosed |
| EP-1140917-B1 | S-OXIDE LIPID LOWERING COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2003-03-26 | — | — | EP | disclosed |
| US-6451802-B1 | S-oxide lipid lowering compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 2002-09-17 | — | — | US | disclosed |
| EP-1220856-A2 | PYRAZOLO[4,3-D]PYRIMIDINE DERIVATIVES | Pfizer Limited (GB) | 2002-07-10 | — | — | EP | disclosed |
| EP-1140917-A1 | S-OXIDE LIPID LOWERING COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2001-10-10 | — | — | EP | disclosed |
| WO-2001027113-A2 | PYRAZOLO `4,3-d! PYRIMIDINE DERIVATIVES | PFIZER LIMITED (GB) | 2001-04-19 | — | — | WO | disclosed |
| WO-2001010216-A1 | ANTIARRHYTHMIC COMPOUNDS | MERCK & CO., INC. (US) | 2001-02-15 | — | — | WO | disclosed |
| WO-2000037463-A1 | S-OXIDE LIPID LOWERING COMPOUNDS | JANSSEN PHARMACEUTICA N.V. (BE) | 2000-06-29 | — | — | WO | disclosed |
| US-4269843-A | NONHABIT-FORMING; ANTAGONIST, ANTAGONISM | SRI INTERNATIONAL (US) | 1981-05-26 | — | — | US | disclosed |
| US-4218454-A | N-αMethylcyclopropylmethyl derivatives of normorphine and noroodeine, and analgesic compositions and methods employing the normorphine derivatives | SRI INTERNATIONAL (US) | 1980-08-19 | — | — | US | disclosed |