SCHEMBL3583058

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6471490	0.86	ALDH1A1 (0.52)	L3MBTL1MAPTKDM4EALDH1A1MEN1
	SCHEMBL5378527	0.81	CYP1A2 (0.52)	EPHX2MAPTKDM4EALDH1A1MEN1
	SCHEMBL3578935	0.79	TLR9 (0.55)	TLR9TLR7EPHX2L3MBTL1MAPT
	SCHEMBL3576150	0.79	KDM4E (0.56)	TLR9TLR7EPHX2MAPTKDM4E
	SCHEMBL3581553	0.78	TLR9 (0.49)	TLR9TLR7EPHX2HRH3NSD2
	SCHEMBL3576635	0.78	HRH3 (0.54)	TLR9TLR7HRH3HTR2A
	SCHEMBL3579866	0.78	HRH3 (0.63)	TLR9TLR7EPHX2MAPTKDM4E
	SCHEMBL3587105	0.78	GPR119 (0.52)	TLR9TLR7EPHX2MAPTKDM4E
	SCHEMBL3579113	0.78	KDM4E (0.55)	TLR9TLR7EPHX2L3MBTL1KDM4E
	SCHEMBL3583503	0.77	HRH3 (0.52)	KDM4EALDH1A1HRH3HTR2AHTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.