Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL422881 | 0.86 | TSHR (0.52) | TSHRALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL29550931 | 0.86 | TSHR (0.52) | TSHRALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL31618845 | 0.85 | TSHR (0.50) | TSHRALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL28704375 | 0.85 | TSHR (0.50) | TSHRALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL22833338 | 0.85 | ALDH1A1 (0.52) | TSHRALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL13072040 | 0.83 | TSHR (0.49) | TSHRALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7958076 | 0.83 | TSHR (0.49) | TSHRALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9355979 | 0.82 | TSHR (0.55) | TSHRALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL334079 | 0.82 | EGFR (0.50) | TSHRKDM4ECA12CA1CA2 | |
| SCHEMBL5664007 | 0.82 | KDM4E (0.57) | TSHRALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120136886-A | PDE4 inhibitor with pyranonaphthyridone skeleton and preparation method and application thereof | 中山大学 | 2025-06-13 | — | — | CN | claimed |
| CN-114163446-A | Quinoline ketone skeleton PDE4 inhibitor and preparation method and application thereof | 中山大学 | 2022-03-11 | — | — | CN | claimed |
| CN-120136886-A | PDE4 inhibitor with pyranonaphthyridone skeleton and preparation method and application thereof | 中山大学 | 2025-06-13 | — | — | CN | disclosed |
| CN-114163446-B | PDE4 inhibitor with quinolinone skeleton and preparation method and application thereof | 中山大学 | 2023-11-21 | — | — | CN | disclosed |
| CN-114163446-A | Quinoline ketone skeleton PDE4 inhibitor and preparation method and application thereof | 中山大学 | 2022-03-11 | — | — | CN | disclosed |
| CN-106316931-B | 2-phenylnicotinic acid derivatives with insecticidal and acaricidal activity | 沈阳中化农药化工研发有限公司 | 2020-05-05 | — | — | CN | disclosed |
| US-20200058883-A1 | ORGANIC ELECTRIC LIGHT EMITTING ELEMENT, MATERIAL FOR SAID ELEMENT, AND LIGHT EMITTING DEVICE, DISPLAY DEVICE, AND ILLUMINATION DEVICE EMPLOYING SAID ELEMENT | UDC IRELAND LTD (IE) | 2020-02-20 | — | — | US | disclosed |
| US-10468607-B2 | Organic electric light emitting element, material for said element, and light emitting device, display device, and illumination device employing said element | UDC IRELAND LIMITED (IE) | 2019-11-05 | — | — | US | disclosed |
| CN-110392681-A | Tosylacetate-based compounds and derivatives thereof as PHGDH inhibitors | 勃林格殷格翰国际有限公司 | 2019-10-29 | — | — | CN | disclosed |
| EP-2734526-B1 | HETEROCYCLIC AMIDE DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2016-04-06 | — | — | EP | disclosed |
| US-9221832-B2 | Heterocyclic amide derivatives as P2X7 receptor antagonists | ACTELION PHARMACEUTICALS LTD. (CH) | 2015-12-29 | — | — | US | disclosed |
| CN-1162957-A | Isoxazole derivatives | SANKYO CO (JP) | 1997-10-22 | — | — | CN | disclosed |
| EP-0779281-A1 | ISOXAZOLES | SANKYO COMPANY LIMITED (JP) | 1997-06-18 | — | — | EP | disclosed |
| EP-0714393-A1 | THIAZOLES AS ANTIVIRAL | PFIZER INC. (US) | 1996-06-05 | — | — | EP | disclosed |
| US-5493028-A | Processes for producing 2-Halo-nicotinic acid derivatives and precursors thereto | REILLY INDUSTRIES, INC. (US) | 1996-02-20 | — | — | US | disclosed |
| WO-1995005378-A1 | ANTIVIRAL THIAZOLES | PFIZER INC. (US) | 1995-02-23 | — | — | WO | disclosed |
| EP-0633880-A1 | PROCESSES FOR PRODUCING 2-HALO-NICOTINIC ACID DERIVATIVES AND PRECURSORS THERETO | REILLY INDUSTRIES, INC. (US) | 1995-01-18 | — | — | EP | disclosed |
| US-5250548-A | Treating hypertension, heart failure | ABBOTT LABORATORIES (US) | 1993-10-05 | — | — | US | disclosed |
| WO-1993018005-A2 | PROCESSES FOR PRODUCING 2-HALO-NICOTINIC ACID DERIVATIVES AND PRECURSORS THERETO | REILLY INDUSTRIES, INC. (US) | 1993-09-16 | — | — | WO | disclosed |
| EP-0475206-A2 | Angiotensin II receptor antagonists | ABBOTT LABORATORIES (US) | 1992-03-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10468607-B2 | Organic electric light emitting element, material for said element, and light emitting device, display device, and illumination device employing said element | L1CAM, NAP1L1, NOTCH1 | TSHR 4611/4885ALDH1A1 120/4885KDM4E 2938/4885 |
| US-20200058883-A1 | ORGANIC ELECTRIC LIGHT EMITTING ELEMENT, MATERIAL FOR SAID ELEMENT, AND LIGHT EMITTING DEVICE, DISPLAY DEVICE, AND ILLUMINATION DEVICE EMPLOYING SAID ELEMENT | NR0B1, NR2E1, NR1D1 | TSHR 3963/4885ALDH1A1 227/4885KDM4E 3180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.