⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3259063 | 0.84 | TSHR (0.62) | — | |
| SCHEMBL1164551 | 0.82 | — | — | |
| SCHEMBL28448129 | 0.80 | — | — | |
| SCHEMBL15760567 | 0.80 | — | — | |
| SCHEMBL4407661 | 0.77 | TSHR (0.59) | — | |
| SCHEMBL13606400 | 0.77 | TSHR (0.59) | — | |
| SCHEMBL4050869 | 0.77 | TSHR (0.42) | — | |
| SCHEMBL25017479 | 0.75 | TSHR (0.58) | — | |
| Sulfuric Acid SCHEMBL30534467 | 0.75 | TSHR (0.53) | — | |
| SCHEMBL1009529 | 0.75 | TSHR (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 230 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250066570-A1 | LAMINATE DEVICE WITH METALLIC AND POLYMER LAYERS | QUANTUM MICROMATERIALS INC (US) | 2025-02-27 | — | — | US | claimed |
| CN-119431324-A | 1- (4/5-Cyano-6-substituted pyrimidine-2-yl) -1H-pyrazole-4-formic acid compound, and preparation method and application thereof | 沈阳药科大学 | 2025-02-14 | — | — | CN | claimed |
| US-20230357578-A1 | AIRTIGHT FILM WITH CERAMIC SEALING LAYER AND POLYMER SEALING LAYER | Quantum MicroMaterials, Inc. | 2023-11-09 | — | — | US | claimed |
| CN-106008519-A | Synthesis method of 5-(4-fluorophenyl)-N-morpholinyl-7-trifluoromethylpyrazolo[1,5-a]pyrimidyl-3-amide | 重庆医药高等专科学校 | 2016-10-12 | — | — | CN | claimed |
| CN-106008518-A | Synthesis method of 5-(4-fluorophenyl)-N-(4-chlorophenyl)-7-trifluoromethylpyrazolo[1,5-a]pyrimidine-3-amide | 重庆医药高等专科学校 | 2016-10-12 | — | — | CN | claimed |
| CN-106008520-A | Synthesis method of 5-arylpyrazolopyrimidine derivatives | 重庆医药高等专科学校 | 2016-10-12 | — | — | CN | claimed |
| CN-106008517-A | Synthesis method of 2-(5-(4-fluorophenyl)-7-trifluoromethylpyrazolo[1,5-a]pyrimidine-3-amide)diethyl glutarate | 重庆医药高等专科学校 | 2016-10-12 | — | — | CN | claimed |
| CN-105949201-A | Synthesis method of 5-(4-fluorophenyl)-N-(4-chlorophenylethyl)-7-trifluoromethylpyrazol[1, 5-a] pyrimidine-3-amide | 重庆医药高等专科学校 | 2016-09-21 | — | — | CN | claimed |
| CN-105949200-A | Method for synthesizing 5-arylpyrazole [1, 5-alpha] pyrimindine derivatives | 重庆医药高等专科学校 | 2016-09-21 | — | — | CN | claimed |
| CN-105949199-A | Synthesis method of 5-(4-fluorophenyl)-N, N-dimethyl-7-trifluoromethylpyrazol[1, 5-a] pyrimidine-3-amide | 重庆医药高等专科学校 | 2016-09-21 | — | — | CN | claimed |
| CN-105949202-A | Synthesis method of 5-(4-fluorophenyl)-N-(3-(dimethylamino) propyl)-7-trifluoromethyl pyrazol[1, 5-a] pyrimidine-3-amide | 重庆医药高等专科学校 | 2016-09-21 | — | — | CN | claimed |
| CN-105884785-A | Synthesis method of ethyl 5-(4-fluorophenyl)-7-trifluoromethylpyrazolo[1,5-a]pyrimidyl-3-carboxylate | 重庆医药高等专科学校 | 2016-08-24 | — | — | CN | claimed |
| CN-105884783-A | Synthesis method of 5-(4-fluorophenyl)-N-1-(3-hydroxyadamantyl)-7-trifluoromethylpyrazolo[1,5-a]pyrimidyl-3-amide | 重庆医药高等专科学校 | 2016-08-24 | — | — | CN | claimed |
| CN-105884784-A | Synthetic method for 5-(4-fluorophenyl)-7-trifluoromethyl[1,5-a] pyrimidine-3-carboxylic acid | 重庆医药高等专科学校 | 2016-08-24 | — | — | CN | claimed |
| EP-1067121-B1 | 5-Aminopyrazole-4-carboxylate derivative and process for preparing the same | MITSUI CHEMICALS INC (JP) | 2008-05-28 | — | — | EP | claimed |
| US-6235911-B1 | 5-aminopyrazole-4-carboxylate derivative and process for preparing the same | MITSUI CHEMICALS, INC. (JP) | 2001-05-22 | — | — | US | claimed |
| CN-1280127-A | 5-aminopyrazole-4-carboxylic ester derivatives and its preparing method | MITSUI CHEMICAL IND CO LTD (JP) | 2001-01-17 | — | — | CN | claimed |
| EP-1067121-A2 | 5-Aminopyrazole-4-carboxylate derivative and process for preparing the same | Mitsui Chemicals, Inc. (JP) | 2001-01-10 | — | — | EP | claimed |
| JP-62158257-A | — | — | None | — | — | JP | disclosed |
| JP-S62158258-A | PRODUCTION OF 5-AMINOPYRAZOLE-4-CARBOXYLATE COMPOUND | KONISHIROKU PHOTO IND CO LTD | 1987-07-14 | — | — | JP | disclosed |