Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | GAA | P10253 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11701238 | 0.80 | TSHR (0.67) | TSHRALDH1A1MEN1KMT2AGAA | |
| SCHEMBL31484057 | 0.80 | TSHR (0.67) | TSHRALDH1A1MEN1KMT2AGAA | |
| SCHEMBL309220 | 0.80 | ALDH1A1 (1.00) | TSHRALDH1A1MEN1KMT2AGAA | |
| SCHEMBL13519179 | 0.78 | TSHR (0.65) | TSHRALDH1A1MEN1KMT2AGAA | |
| SCHEMBL12233266 | 0.78 | TSHR (0.65) | TSHRALDH1A1MEN1KMT2AGAA | |
| SCHEMBL15760567 | 0.78 | — | — | |
| SCHEMBL3259063 | 0.77 | TSHR (0.62) | TSHRALDH1A1MEN1KMT2AGAA | |
| SCHEMBL29438437 | 0.77 | TSHR (0.62) | TSHRALDH1A1MEN1KMT2AGAA | |
| SCHEMBL18035909 | 0.77 | TSHR (0.62) | TSHRALDH1A1MEN1KMT2AGAA | |
| SCHEMBL19120364 | 0.77 | TSHR (0.62) | TSHRALDH1A1MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4710923-A2 | INDOLE AHR INHIBITORS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| EP-4219501-B1 | COMPOUND CONTAINING 2,4-THIAZOLE RING, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | UNIV SHANDONG (CN) | 2026-01-28 | — | — | EP | disclosed |
| EP-3612030-B1 | INDOLE AHR INHIBITORS AND USES THEREOF | IKENA ONCOLOGY INC (US) | 2025-12-24 | — | — | EP | disclosed |
| US-20250122205-A1 | INDOLE AHR INHIBITORS AND USES THEREOF | PAHR THERAPEUTICS, INC. | 2025-04-17 | — | — | US | disclosed |
| US-20250121073-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2025-04-17 | — | — | US | disclosed |
| US-12150995-B2 | IRAK degraders and uses thereof | KYMERA THERAPEUTICS, INC. (US) | 2024-11-26 | — | — | US | disclosed |
| US-12077542-B2 | Indole AHR inhibitors and uses thereof | Ikena Oncology, Inc. (US) | 2024-09-03 | — | — | US | disclosed |
| US-20230391783-A1 | COMPOUND CONTAINING 2,4-THIAZOLE RING, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | SHANDONG UNIVERSITY (CN) | 2023-12-07 | — | — | US | disclosed |
| EP-4271664-A1 | IRAK DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2023-11-08 | — | — | EP | disclosed |
| CN-110831600-B | Indole AHR inhibitors and uses thereof | 医肯纳肿瘤学公司 | 2023-10-17 | — | — | CN | disclosed |
| US-5036064-A | Antibiotics | HOFFMANN-LA ROCHE INC. (US) | 1991-07-30 | — | — | US | disclosed |
| EP-0286145-A2 | 3-Heterocyclylthiomethyl cephalosporins | SANKEI PHARMACEUTICAL COMPANY LIMITED (JP) | 1988-10-12 | — | — | EP | disclosed |
| US-4459229-A | Heterocyclic azo dyes with couplers having sulfoaralkyl groups | EASTMAN KODAK COMPANY (US) | 1984-07-10 | — | — | US | disclosed |
| EP-0017558-B1 | HETEROCYCLIC AZO COMPOUNDS HAVING SULFATE GROUPS | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1983-10-05 | — | — | EP | disclosed |
| US-4301069-A | COLORFAST DYES FOR WOOL, CELLULOSE ACETATE, AND POLYAMIDES | EASTMAN KODAK COMPANY (US) | 1981-11-17 | — | — | US | disclosed |
| US-4282144-A | VIOLET TO BLUE DYE SHADES FOR POLYAMIDES | EASTMAN KODAK COMPANY (US) | 1981-08-04 | — | — | US | disclosed |
| US-4255326-A | MONOAZO DYES; THIOPHENE DYES; POLYAMIDES, CELLULOSE ACETATE AND WOOL | EASTMAN KODAK COMPANY (US) | 1981-03-10 | — | — | US | disclosed |
| EP-0020161-A2 | Azodyestuffs derived from 5-membered heterocyclic amines and aromatic couplers containing sulpho-groups, or salts thereof and their use in dyeing polyamide fibres | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1980-12-10 | — | — | EP | disclosed |
| EP-0017558-A1 | Heterocyclic azo compounds having sulfate groups | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1980-10-15 | — | — | EP | disclosed |
| US-4006127-A | Cationic diazacyanine dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1977-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250121073-A1 | IRAK DEGRADERS AND USES THEREOF | IRAK2, IRAK3, IRAK1 | TSHR 3319/4885ALDH1A1 2776/4885MEN1 4055/4885 |
| US-20250122205-A1 | INDOLE AHR INHIBITORS AND USES THEREOF | AHR, ARNT, IDO1 | TSHR 974/4885ALDH1A1 316/4885MEN1 4767/4885 |
| US-12150995-B2 | IRAK degraders and uses thereof | IRAK2, IRAK3, IRAK1 | TSHR 3319/4885ALDH1A1 2776/4885MEN1 4055/4885 |
| US-20230391783-A1 | COMPOUND CONTAINING 2,4-THIAZOLE RING, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | CYP4F11, CYP4A11, CYP4F8 | TSHR 422/4885ALDH1A1 572/4885MEN1 921/4885 |
| US-12077542-B2 | Indole AHR inhibitors and uses thereof | AHR, ARNT, IDO1 | TSHR 974/4885ALDH1A1 316/4885MEN1 4767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.