Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.40 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | VNN1 | O95497 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3583852 | 0.92 | LPAR1 (0.41) | CNR1LPAR1LPAR5TRPV1P2RX1 | |
| SCHEMBL3583799 | 0.91 | CNR1 (0.40) | CNR1LPAR1LPAR5TRPV1P2RX1 | |
| SCHEMBL3576346 | 0.91 | CNR1 (0.38) | CNR1LPAR1LPAR5TRPV1P2RX1 | |
| SCHEMBL3581404 | 0.90 | CNR1 (0.43) | CNR1LPAR1LPAR5TRPV1P2RX1 | |
| SCHEMBL3571600 | 0.88 | LMNA (0.42) | CNR1LPAR1LPAR5ATMC5AR1 | |
| SCHEMBL3575607 | 0.88 | CNR1 (0.40) | CNR1LPAR1LPAR5TRPV1P2RX1 | |
| SCHEMBL3581190 | 0.88 | TRPV1 (0.41) | CNR1LPAR1LPAR5TRPV1ATM | |
| SCHEMBL3574145 | 0.87 | SCN9A (0.39) | CNR1LPAR1LPAR5P2RX1KDM5A | |
| SCHEMBL3587845 | 0.87 | LPAR1 (0.42) | CNR1LPAR1LPAR5TRPV1P2RX1 | |
| SCHEMBL3573725 | 0.86 | CNR1 (0.38) | CNR1LPAR1LPAR5TRPV1P2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |