Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 3/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.38 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3584423 | 0.88 | LPAR1 (0.43) | LPAR1LPAR5C5AR1LPAR2SLC2A1 | |
| SCHEMBL3576810 | 0.88 | LMNA (0.42) | LPAR1LPAR5CNR1C5AR1ATM | |
| SCHEMBL3583813 | 0.87 | CNR1 (0.41) | LPAR1LPAR5CNR1PPARGPPARD | |
| SCHEMBL3581404 | 0.87 | CNR1 (0.43) | LPAR1LPAR5CNR1PPARGPPARD | |
| SCHEMBL3583852 | 0.85 | LPAR1 (0.41) | LPAR1LPAR5CNR1PPARGPPARD | |
| SCHEMBL12520790 | 0.85 | LPAR1 (0.47) | LPAR1LPAR5CNR1PPARGPPARD | |
| SCHEMBL3583799 | 0.85 | CNR1 (0.40) | LPAR1LPAR5CNR1PPARGPPARD | |
| SCHEMBL3574025 | 0.84 | C5AR1 (0.46) | LPAR1LPAR5CNR1C5AR1CA12 | |
| SCHEMBL1387045 | 0.83 | LPAR1 (0.38) | LPAR1LPAR5CNR1PPARGPPARD | |
| SCHEMBL3576346 | 0.83 | CNR1 (0.38) | LPAR1LPAR5CNR1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |