Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 11/20 | 0.47 |
| ▸ | PPARG | P37231 | 7/20 | 0.46 |
| ▸ | PPARD | Q03181 | 7/20 | 0.46 |
| ▸ | PPARA | Q07869 | 7/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11295948 | 0.94 | GPR84 (0.55) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL5978598 | 0.92 | GPR84 (0.58) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL1768615 | 0.92 | GPR84 (0.58) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL11293085 | 0.92 | GPR84 (0.58) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL11290033 | 0.92 | GPR84 (0.58) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL8528115 | 0.92 | GPR84 (0.58) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL1768763 | 0.92 | GPR84 (0.58) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL26679462 | 0.92 | AKR1B1 (0.54) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL10707793 | 0.91 | GPR84 (0.54) | CA2AKR1B1GPR84PPARGPPARD | |
| SCHEMBL11287170 | 0.90 | FFAR4 (0.58) | AKR1B1GPR84PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101111551-A | Co-additive composition and method of applying same to nucleated polymer compounds | MILLIKEN & CO (US) | 2008-01-23 | — | — | CN | claimed |
| EP-0060224-A1 | Corrosion protecting composition | CIBA-GEIGY AG (CH) | 1982-09-15 | — | — | EP | claimed |
| US-8455413-B2 | Additive for oils and lubricant comprising the same | KH NEOCHEM CO., LTD. (JP) | 2013-06-04 | — | — | US | disclosed |
| CN-101029120-B | Melt-processable polyurethanes and process for their preparation | BAYER MATERIALSCIENCE AG | 2011-06-15 | — | — | CN | disclosed |
| US-7842822-B2 | Substituted benzopyrans as selective estrogen receptor-beta agonists | ELI LILLY AND COMPANY (US) | 2010-11-30 | — | — | US | disclosed |
| US-20100298183-A1 | ADDITIVE FOR OILS AND LUBRICANT COMPRISING THE SAME | KYOWA HAKKO CHEMICAL CO., LTD. (JP) | 2010-11-25 | — | — | US | disclosed |
| US-20090298925-A1 | SUBSTITUTED BENZOPYRANS AS SELECTIVE ESTROGEN RECEPTOR-BETA AGONISTS | DURST GREGORY LEE | 2009-12-03 | — | — | US | disclosed |
| CN-101029120-A | Melt-processable polyurethanes and process for their preparation | BAYER MATERIALSCIENCE AG (DE) | 2007-09-05 | — | — | CN | disclosed |
| US-4457924-A | PENICILLINS, OXAPENICILLINS, BETA-LACTAMASE INHIBITORS | PFIZER, INC. (US) | 1984-07-03 | — | — | US | disclosed |
| EP-0060224-A1 | Corrosion protecting composition | CIBA-GEIGY AG (CH) | 1982-09-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298183-A1 | ADDITIVE FOR OILS AND LUBRICANT COMPRISING THE SAME | NCOA2, NCOR2, NR1H2 | CA2 3034/4885AKR1B1 590/4885GPR84 67/4885 |
| US-20090298925-A1 | SUBSTITUTED BENZOPYRANS AS SELECTIVE ESTROGEN RECEPTOR-BETA AGONISTS | GPER1, ESR2, ESR1 | CA2 2419/4885AKR1B1 271/4885GPR84 51/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.