Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 15/20 | 0.80 |
| ▸ | CA2 | P00918 | 15/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.74 |
| ▸ | CA12 | O43570 | 12/20 | 0.69 |
| ▸ | CA9 | Q16790 | 12/20 | 0.69 |
| ▸ | CA7 | P43166 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | CA4 | P22748 | 1/20 | 0.62 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.62 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetylsulfanilamide SCHEMBL7429740 | 0.85 | CA1 (0.76) | CA1CA2KMT2ACA12CA9 | |
| SCHEMBL28499329 | 0.85 | KMT2A (1.00) | CA1CA2KMT2ACA12CA9 | |
| SCHEMBL6990778 | 0.83 | KMT2A (0.74) | CA1CA2KMT2ACA12CA9 | |
| SCHEMBL3893567 | 0.83 | CA1 (0.59) | CA1CA2KMT2ACA12CA9 | |
| SCHEMBL27850953 | 0.83 | CA1 (0.68) | CA1CA2CA12CA9CA7 | |
| SCHEMBL5062623 | 0.82 | PEPD (0.80) | CA1CA2KMT2AMEN1 | |
| SCHEMBL1517568 | 0.82 | KMT2A (0.66) | CA1CA2KMT2ACA12CA9 | |
| SCHEMBL7759448 | 0.82 | TGM2 (0.61) | CA1CA2KMT2ACA12CA9 | |
| SCHEMBL3893212 | 0.82 | CA1 (0.57) | CA1CA2KMT2ACA12CA9 | |
| SCHEMBL1034515 | 0.82 | NPC1 (0.59) | CA1CA2KMT2ACA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101243063-A | Sulfonamide derivatives having carbonic anhydrase inhibiting activity and their use as therapeutic and diagnostic agents | UNION LIFE SCIENCE LTD (GB) | 2008-08-13 | — | — | CN | claimed |
| CN-110128483-B | Carbonic anhydrase targeted tetravalent platinum complex and preparation method and application thereof | 中山大学 | 2021-01-15 | — | — | CN | disclosed |
| CN-109791361-A | Positive lithographic printing plate precursor, method for producing same, and method for producing lithographic printing plate | 富士胶片株式会社 | 2019-05-21 | — | — | CN | disclosed |
| CN-102300844-B | Sulfamoyl-phenyl-ureidobenzamidine derivatives as antimalarial agents | 4SC AG | 2015-03-11 | — | — | CN | disclosed |
| CN-102971295-A | Chemical compounds | SYNGENTA LTD | 2013-03-13 | — | — | CN | disclosed |
| EP-2013211-B1 | PURINE DERIVATIVES FOR USE AS ADENOSIN A2A RECEPTOR AGONISTS | NOVARTIS AG (CH) | 2012-03-14 | — | — | EP | disclosed |
| CN-102300844-A | Sulfamoyl-phenyl-ureidobenzamidine derivatives as antimalarial agents | — | 2011-12-28 | — | — | CN | disclosed |
| CN-101243063-A | Sulfonamide derivatives having carbonic anhydrase inhibiting activity and their use as therapeutic and diagnostic agents | UNION LIFE SCIENCE LTD (GB) | 2008-08-13 | — | — | CN | disclosed |
| WO-2007121920-A2 | PURINE DERIVATIVES FOR USE AS ADENOSIN A2A RECEPTOR AGONISTS | NOVARTIS AG (CH) | 2007-11-01 | — | — | WO | disclosed |