⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5049787 | 0.72 | — | — | |
| SCHEMBL94370 | 0.72 | — | — | |
| SCHEMBL5499623 | 0.72 | — | — | |
| SCHEMBL29113360 | 0.69 | — | — | |
| SCHEMBL20365804 | 0.69 | ALDH1A1 (0.38) | — | |
| SCHEMBL11145636 | 0.69 | — | — | |
| SCHEMBL25416416 | 0.67 | — | — | |
| SCHEMBL3366786 | 0.67 | — | — | |
| SCHEMBL64898 | 0.67 | — | — | |
| SCHEMBL10155539 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8202876-B2 | Compounds and compositions as protein kinase inhibitors | IRM LLC (BM) | 2012-06-19 | — | — | US | claimed |
| CN-1918158-B | Compounds and compositions as protein kinase inhibitors | IRM LLC | 2011-03-02 | — | — | CN | claimed |
| US-20100029605-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2010-02-04 | — | — | US | claimed |
| CN-101522661-A | Compounds and compositions as protein kinase inhibitors | IRM LLC (VG) | 2009-09-02 | — | — | CN | claimed |
| EP-2057146-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2009-05-13 | — | — | EP | claimed |
| WO-2008042639-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2008-04-10 | — | — | WO | claimed |
| CN-1918158-A | Compounds and compositions as protein kinase inhibitors | IRM LLC (BM) | 2007-02-21 | — | — | CN | claimed |
| CN-1415617-A | Compound possessing function for preventing and curing atherosclerosis and its application in biologic pharmacological science | INST OF TOXICANT AND MEDICAMEN (CN) | 2003-05-07 | — | — | CN | claimed |
| CN-1415619-A | Compound for adjusting functional activity of vascular endothelial cell, its preparation method as well as usage | INST OF TOXICANT AND MEDICAMEN (CN) | 2003-05-07 | — | — | CN | claimed |
| CN-1415618-A | Compound possessing function for preventing and curing thrombus disease, its pharmacy compsn. and usage in medication | INST OF TOXICANT AND MEDICAMEN (CN) | 2003-05-07 | — | — | CN | claimed |
| US-4374846-A | N-Amino alkyl indole compounds compositions containing same, and a method of using same in therapy of disorders of gastrointestinal motility | KALI-CHEMIE PHARMA GMBH (DE) | 1983-02-22 | — | — | US | claimed |
| CN-101522657-B | STAT3/5 activation inhibitor | OTSUKA PHARMACEUTICAL CO.,LTD. (JP) | 2014-10-15 | — | — | CN | disclosed |
| CN-103224488-A | Heterocyclic compound or salt thereof | OTSUKA PHARMA CO LTD | 2013-07-31 | — | — | CN | disclosed |
| CN-1993339-B | Aromatic compound | OTSUKA PHARMA CO LTD | 2013-05-22 | — | — | CN | disclosed |
| CN-102844886-A | Use of indanthrene compounds in organic photovoltaics | BASF SE | 2012-12-26 | — | — | CN | disclosed |
| CN-1098716-A | Vasopressin antagonists and oxytocin antagonists | OTSUKA CHEMICAL CO LTD (JP) | 1995-02-15 | — | — | CN | disclosed |
| CN-1091288-A | The oxytocin antagonist | OTSUKA PHARMA CO LTD (JP) | 1994-08-31 | — | — | CN | disclosed |
| EP-0450097-A1 | BENZOHETEROCYCLIC COMPOUNDS. | OTSUKA PHARMA CO LTD (JP) | 1991-10-09 | — | — | EP | disclosed |
| WO-1991005549-A1 | BENZOHETEROCYCLIC COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-02 | — | — | WO | disclosed |
| CN-1051038-A | BENZOHETEROCYCLIC COMPOUNDS | OTSUKA PHARMA CO LTD (JP) | 1991-05-01 | — | — | CN | disclosed |