Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10172410 | 0.94 | PARP1 (0.32) | PARP1PARP2 | |
| SCHEMBL360327 | 0.94 | PARP1 (0.34) | PARP1PARP2 | |
| SCHEMBL12503367 | 0.85 | PARP1 (0.37) | PARP1PARP2CYP2D6 | |
| SCHEMBL359582 | 0.84 | PARP1 (0.48) | PARP1PARP2 | |
| SCHEMBL10173013 | 0.81 | RAD52 (0.43) | PARP1 | |
| SCHEMBL358818 | 0.80 | RAD52 (0.46) | PARP1 | |
| SCHEMBL12503399 | 0.78 | PARP1 (0.37) | PARP1PARP2 | |
| SCHEMBL10172411 | 0.78 | PARP1 (0.46) | PARP1PARP2 | |
| SCHEMBL359165 | 0.77 | PARP1 (0.49) | PARP1PARP2 | |
| SCHEMBL27917165 | 0.74 | PABPC1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012006958-A1 | AMIDS SUBSTITUTED INDAZOLE DERIVATIVEES AS PLOY(ADP-RIBOSE)POLYMERASE INHIBITORS | ZHEJIANG BETA PHARMA INC. (CN) | 2012-01-19 | — | — | WO | claimed |
| WO-2012006958-A1 | AMIDS SUBSTITUTED INDAZOLE DERIVATIVEES AS PLOY(ADP-RIBOSE)POLYMERASE INHIBITORS | ZHEJIANG BETA PHARMA INC. (CN) | 2012-01-19 | — | — | WO | disclosed |