Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL358657 | 0.94 | PARP1 (0.34) | PARP1PARP2 | |
| SCHEMBL10172410 | 0.88 | PARP1 (0.32) | PARP1PARP2 | |
| SCHEMBL358818 | 0.86 | RAD52 (0.46) | PARP1RAD52 | |
| SCHEMBL12503399 | 0.84 | PARP1 (0.37) | PARP1PARP2 | |
| SCHEMBL359165 | 0.83 | PARP1 (0.49) | PARP1PARP2 | |
| SCHEMBL12503367 | 0.78 | PARP1 (0.37) | PARP1PARP2 | |
| SCHEMBL359582 | 0.77 | PARP1 (0.48) | PARP1PARP2 | |
| SCHEMBL10173013 | 0.75 | RAD52 (0.43) | PARP1RAD52 | |
| SCHEMBL27917078 | 0.73 | PABPC1 (0.32) | — | |
| SCHEMBL10172541 | 0.72 | RAD52 (0.30) | PARP1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012006958-A1 | AMIDS SUBSTITUTED INDAZOLE DERIVATIVEES AS PLOY(ADP-RIBOSE)POLYMERASE INHIBITORS | ZHEJIANG BETA PHARMA INC. (CN) | 2012-01-19 | — | — | WO | claimed |
| WO-2012006958-A1 | AMIDS SUBSTITUTED INDAZOLE DERIVATIVEES AS PLOY(ADP-RIBOSE)POLYMERASE INHIBITORS | ZHEJIANG BETA PHARMA INC. (CN) | 2012-01-19 | — | — | WO | disclosed |
| WO-2012006958-A1 | AMIDS SUBSTITUTED INDAZOLE DERIVATIVEES AS PLOY(ADP-RIBOSE)POLYMERASE INHIBITORS | ZHEJIANG BETA PHARMA INC. (CN) | 2012-01-19 | — | — | WO | disclosed |