Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.47 |
| ▸ | ACACB | O00763 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.38 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.38 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.38 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.38 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.38 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.38 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.38 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3581799 | 0.87 | CNR1 (0.51) | CNR1EPHX1ACACBPPARGPPARA | |
| SCHEMBL3273907 | 0.82 | EPHX1 (0.50) | EPHX1ESR1ESR2HTTADCY6 | |
| Hydrochloric Acid SCHEMBL4026086 | 0.81 | EPHX1 (0.49) | EPHX1ESR1ESR2HTTADCY6 | |
| SCHEMBL5601428 | 0.81 | MAPT (0.47) | EPHX1ACACBHTTMAOBPARP10 | |
| SCHEMBL3581268 | 0.78 | EPHX1 (0.48) | EPHX1ACACBADCY6ADCY3ADCY9 | |
| SCHEMBL3578665 | 0.78 | EPHX1 (0.44) | CNR1EPHX1MAOBPPARGPPARA | |
| SCHEMBL21959089 | 0.77 | EPHX1 (0.57) | EPHX1ESR1ESR2HTTPARP10 | |
| SCHEMBL28151669 | 0.77 | EPHX1 (0.77) | EPHX1PPARGPPARACNR2 | |
| SCHEMBL28835702 | 0.77 | EPHX1 (0.77) | EPHX1PTPN1PPARGPPARA | |
| SCHEMBL4946470 | 0.76 | PTPN1 (0.52) | EPHX1ACACBPTPN1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |