Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 11/20 | 0.51 |
| ▸ | CNR2 | P34972 | 7/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 5/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3586614 | 0.87 | CNR1 (0.47) | CNR1CNR2EPHX1PPARAPPARG | |
| SCHEMBL3942501 | 0.82 | EPHX1 (0.50) | CNR1EPHX1CYP1A2MEN1CYP2C19 | |
| SCHEMBL2356411 | 0.78 | EPHX1 (0.65) | CNR2EPHX1PPARAPPARG | |
| SCHEMBL28108267 | 0.77 | EPHX1 (0.77) | CNR1CNR2EPHX1PPARACYP1A2 | |
| SCHEMBL21959089 | 0.77 | EPHX1 (0.57) | EPHX1PPARACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL28108266 | 0.77 | EPHX1 (0.77) | CNR1CNR2EPHX1PPARAMEN1 | |
| SCHEMBL3578665 | 0.76 | EPHX1 (0.44) | CNR1EPHX1PPARAPPARG | |
| SCHEMBL3581268 | 0.76 | EPHX1 (0.48) | EPHX1ACACB | |
| SCHEMBL4946470 | 0.76 | PTPN1 (0.52) | EPHX1PPARAPPARGACACB | |
| SCHEMBL4946473 | 0.76 | PTPN1 (0.52) | EPHX1PPARAPPARGACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |