Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.39 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.39 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.39 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.39 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.39 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.39 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.39 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3272260 | 0.89 | TRPM8 (0.45) | EPHX1TRPM8FFAR1ADCY6ADCY3 | |
| SCHEMBL3578665 | 0.86 | EPHX1 (0.44) | EPHX1TRPM8FFAR1 | |
| SCHEMBL5187771 | 0.84 | TRPM8 (0.45) | EPHX1TRPM8FFAR1MRGPRX4MME | |
| SCHEMBL3584101 | 0.84 | TRPM8 (0.45) | EPHX1TRPM8FFAR1MMEGPR139 | |
| SCHEMBL5175895 | 0.84 | EPHX1 (0.50) | EPHX1TRPM8FFAR1 | |
| SCHEMBL28107953 | 0.83 | EPHX1 (0.65) | EPHX1TRPM8ACACBFFAR1GRIN2B | |
| SCHEMBL5177434 | 0.82 | EPHX1 (0.47) | EPHX1TRPM8FFAR1MME | |
| SCHEMBL3586614 | 0.78 | CNR1 (0.47) | EPHX1ACACBFFAR1ADCY6ADCY3 | |
| SCHEMBL3272981 | 0.78 | EPHX1 (0.45) | EPHX1ACACBGCGR | |
| SCHEMBL28108268 | 0.78 | EPHX1 (0.65) | EPHX1TRPM8GRIN2BMRGPRX4ADCY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |