Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 8/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3596861 | 0.92 | TAAR1 (0.47) | DPP4TAAR1DPP8PNMTHTR6 | |
| SCHEMBL3604955 | 0.92 | DPP4 (0.48) | DPP4DPP8CXCR2CNR1CYP3A4 | |
| SCHEMBL3586450 | 0.90 | TAAR1 (0.42) | DPP4TAAR1DPP8PNMTHTR6 | |
| SCHEMBL3600802 | 0.89 | DPP4 (0.44) | DPP4DPP8CXCR2CNR1 | |
| SCHEMBL3583003 | 0.87 | DPP4 (0.42) | DPP4DPP8CXCR2CYP3A4 | |
| SCHEMBL3600269 | 0.85 | DPP4 (0.41) | DPP4DPP8CXCR2CNR1CYP3A4 | |
| SCHEMBL3602753 | 0.85 | DPP4 (0.41) | DPP4DPP8CXCR2CNR1MAPT | |
| SCHEMBL3585733 | 0.85 | DPP4 (0.46) | DPP4DPP8CXCR2CNR1CYP3A4 | |
| SCHEMBL3606760 | 0.85 | DPP4 (0.44) | DPP4DPP8CNR1CYP3A4 | |
| SCHEMBL3096850 | 0.84 | DPP4 (0.44) | DPP4DPP8CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728146-B2 | Enzyme inhibitors | PROBIODRUG AG (DE) | 2010-06-01 | — | — | US | claimed |