Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | MARS1 | P56192 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.38 |
| ▸ | ROS1 | P08922 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3084749 | 0.89 | P2RX7 (0.46) | DPP4DPP8DPP9P2RX7MARS1 | |
| SCHEMBL3604955 | 0.88 | DPP4 (0.48) | DPP4DPP8DPP9CYP3A4KCNH2 | |
| SCHEMBL3586864 | 0.87 | DPP4 (0.45) | DPP4DPP8CYP3A4CXCR2 | |
| SCHEMBL3600802 | 0.85 | DPP4 (0.44) | DPP4DPP8CXCR2 | |
| SCHEMBL3585733 | 0.81 | DPP4 (0.46) | DPP4DPP8DPP9CYP3A4KCNH2 | |
| SCHEMBL3602753 | 0.81 | DPP4 (0.41) | DPP4DPP8CXCR2IDO1 | |
| SCHEMBL3606760 | 0.81 | DPP4 (0.44) | DPP4DPP8DPP9CYP3A4 | |
| SCHEMBL3600269 | 0.81 | DPP4 (0.41) | DPP4DPP8CYP3A4CXCR2 | |
| SCHEMBL3096850 | 0.81 | DPP4 (0.44) | DPP4DPP8CYP3A4 | |
| SCHEMBL3595072 | 0.81 | DPP4 (0.46) | DPP4DPP8DPP9MARS1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728146-B2 | Enzyme inhibitors | PROBIODRUG AG (DE) | 2010-06-01 | — | — | US | claimed |