Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 4/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | UBE2N | P61088 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3596861 | 0.93 | TAAR1 (0.47) | TAAR1HTR6DPP4DPP8CXCR2 | |
| SCHEMBL3586864 | 0.90 | DPP4 (0.45) | TAAR1HTR6DPP4DPP8CXCR2 | |
| SCHEMBL3604583 | 0.85 | CNR1 (0.41) | TAAR1DPP4DPP8CNR1KDM4C | |
| SCHEMBL3604955 | 0.82 | DPP4 (0.48) | DPP4DPP8CXCR2CNR1HTT | |
| SCHEMBL3600802 | 0.79 | DPP4 (0.44) | DPP4DPP8CXCR2CNR1 | |
| SCHEMBL3595338 | 0.79 | PNMT (0.41) | TAAR1HTR6DPP4DPP8CXCR2 | |
| SCHEMBL3600855 | 0.78 | DPP4 (0.45) | DPP4DPP8KDM4C | |
| SCHEMBL3585733 | 0.78 | DPP4 (0.46) | DPP4DPP8CXCR2CNR1SMN1; SMN2 | |
| SCHEMBL3596995 | 0.78 | SLC6A4 (0.41) | DPP4DPP8LMNAMAPT | |
| SCHEMBL3583003 | 0.77 | DPP4 (0.42) | DPP4DPP8CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728146-B2 | Enzyme inhibitors | PROBIODRUG AG (DE) | 2010-06-01 | — | — | US | claimed |