SCHEMBL3587054

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3572659	0.86	GABRA2 (0.60)	GABRA2GABRB2PTGS2
	SCHEMBL3586166	0.83	GABRA2 (0.56)	GABRA2GABRB2PTGS2MLYCDTGFBR1
	SCHEMBL13437658	0.83	GABRA2 (0.83)	GABRA2GABRB2PTGS2MLYCDLMNA
	SCHEMBL13437646	0.81	GABRA2 (0.83)	GABRA2GABRB2PTGS2MLYCD
	SCHEMBL3584615	0.78	GABRA2 (0.61)	GABRA2GABRB2PTGS2MLYCDTGFBR1
	SCHEMBL4512242	0.77	GABRA2 (0.68)	GABRA2GABRB2PTGS2
	SCHEMBL16553557	0.77	NR1H2 (0.63)	GABRA2GABRB2PTGS2MLYCDNR1H2
	SCHEMBL6533838	0.76	GABRA2 (0.72)	GABRA2GABRB2PTGS2
	SCHEMBL5336123	0.76	GABRA2 (0.72)	GABRA2GABRB2PTGS2
	SCHEMBL5445432	0.76	GABRA2 (0.66)	GABRA2GABRB2PTGS2MLYCDTGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.