Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 10/20 | 0.72 |
| ▸ | GABRB2 | P47870 | 10/20 | 0.72 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.62 |
| ▸ | CNR1 | P21554 | 9/20 | 0.58 |
| ▸ | CNR2 | P34972 | 5/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5336123 | 1.00 | GABRA2 (0.72) | GABRA2GABRB2PTGS2CNR1CNR2 | |
| SCHEMBL3572659 | 0.91 | GABRA2 (0.60) | GABRA2GABRB2PTGS2CNR1CNR2 | |
| SCHEMBL6336459 | 0.91 | GABRA2 (0.69) | GABRA2GABRB2PTGS2CNR1CNR2 | |
| SCHEMBL1437318 | 0.89 | GABRA2 (0.76) | GABRA2GABRB2PTGS2 | |
| SCHEMBL4479830 | 0.88 | GABRA2 (0.72) | GABRA2GABRB2PTGS2CNR1CNR2 | |
| SCHEMBL6332585 | 0.84 | GABRA2 (0.69) | GABRA2GABRB2PTGS2CNR1CNR2 | |
| SCHEMBL6335259 | 0.83 | CNR1 (0.55) | GABRA2GABRB2CNR1CNR2 | |
| SCHEMBL6334591 | 0.83 | CNR1 (0.64) | CNR1CNR2 | |
| SCHEMBL6335073 | 0.83 | CNR1 (0.64) | GABRA2GABRB2CNR1CNR2 | |
| SCHEMBL4512242 | 0.82 | GABRA2 (0.68) | GABRA2GABRB2PTGS2CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005061504-A1 | BICYCLIC PYRIDAZINONE CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2005-07-07 | — | — | WO | disclosed |