SCHEMBL358730

SCHEMBL358730

O=[N+]([O-])c1cc(Cl)ccc1Cl

nearest known ligand 0.69

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.69
TSHR P16473 1/20 0.69
VCAM1 P19320 9/20 0.60
TDP1 Q9NUW8 1/20 0.54
L3MBTL1 Q9Y468 2/20 0.53
ALDH1A1 P00352 1/20 0.53
P2RX1 P51575 1/20 0.53
PDE7A Q13946 1/20 0.51
PDE7B Q9NP56 1/20 0.51
KIF18A Q8NI77 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29394047 1.00 MAPK1 (0.69) MAPK1TSHRVCAM1TDP1L3MBTL1
Ammonia Solution, Strong SCHEMBL28805237 0.98 MAPK1 (0.67) MAPK1TSHRVCAM1TDP1L3MBTL1
Formic Acid SCHEMBL28068490 0.90 VCAM1 (0.61) MAPK1TSHRVCAM1TDP1L3MBTL1
4-Chloro-2-Nitroaniline SCHEMBL28131921 0.89 TDP1 (0.56) MAPK1TSHRVCAM1TDP1ALDH1A1
Dinitrochlorobenzene SCHEMBL8970951 0.86 TSHR (0.58) MAPK1TSHRVCAM1TDP1ALDH1A1
Phenol SCHEMBL28068489 0.86 VCAM1 (0.56) MAPK1TSHRVCAM1L3MBTL1ALDH1A1
SCHEMBL1524058 0.84 MAPK1 (0.72) MAPK1TSHRVCAM1TDP1L3MBTL1
SCHEMBL487215 0.82 TSHR (1.00) MAPK1TSHRVCAM1TDP1L3MBTL1
SCHEMBL29398960 0.82 TSHR (1.00) MAPK1TSHRVCAM1TDP1L3MBTL1
SCHEMBL6125034 0.82 MAPK1 (0.63) MAPK1TSHRVCAM1TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1449 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025120375-A1 A PROCESS FOR THE PREPARATION OF HERBICIDE INTERMEDIATES GHARDA CHEMICALS LIMITED (IN) 2025-06-12 WO claimed
CN-221245154-U Proportioning device is used in production of 2, 5-dichloronitrobenzene 湖北丰杯生物科技有限公司 2024-07-02 CN claimed
CN-221016002-U Solid-liquid separation device for 2, 5-dichloronitrobenzene 江苏隆昌化工有限公司 2024-05-28 CN claimed
CN-117800808-A Preparation method of 2, 4-dichloro fluorobenzene 帕潘纳(北京)科技有限公司 2024-04-02 CN claimed
CN-220530906-U Filtering device for 2, 5-dichloronitrobenzene production 江苏隆昌化工有限公司 2024-02-27 CN claimed
CN-117050524-A Wear-resistant amphiphobic polyphenylene sulfide composite material and preparation method thereof 江西聚真科技发展有限公司 2023-11-14 CN claimed
CN-116948202-A Preparation method of amphiphobic modified polyphenylene sulfide 江西聚真科技发展有限公司 2023-10-27 CN claimed
CN-116444353-B Preparation method of 4,4' -dichloro-2-hydroxydiphenyl ether 山东奥友化学有限责任公司 2023-09-08 CN claimed
CN-219615527-U Crude production device for 2,4 '-trichloro-2' -nitrodiphenyl ether 山东奥友生物科技股份有限公司 2023-09-01 CN claimed
CN-116444353-A Preparation method of 4,4' -dichloro-2-hydroxydiphenyl ether 山东奥友化学有限责任公司 2023-07-18 CN claimed
EP-0110559-A1 Process for the preparation of 4-chloro-2-nitrobenzonitrile SANWA KAGAKU KENKYUSHO CO., LTD. (JP) 1984-06-13 EP claimed
EP-0073105-A1 Hydrogenation process E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-03-02 EP claimed
US-4232552-A THERMOCHROMISM, DISPOSABLE THERMOMETERS AKZONA INCORPORATED (US) 1980-11-11 US claimed
US-4230637-A Process for the preparation of chlorine-substituted aromatic amines BAYER AKTIENGESELLSCHAFT (DE) 1980-10-28 US claimed
US-4212824-A PLATINUM, IRON OXIDE OR HYDROXIDE ON CARBON BLACK E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-07-15 US claimed
US-4207261-A Process for preparing o-phenylenediamine MAGYAR ASVANYOLAJ ES FOLDGAZ KISERLETI INTEZET (HU) 1980-06-10 US claimed
EP-0000805-A1 Catalytic hydrogenation process for the manufacture of chlorinated aromatic amines The Clayton Aniline Company Limited (GB) 1979-02-21 EP claimed
US-4070401-A HYDROGENATION, DEHALOGENATION INHIBITOR MITSUI TOATSU CHEMICALS INC. (JA) 1978-01-24 US claimed
US-4020107-A ACIDIC PHOSPHORUS COMPOUND DEHALOGENATION INHIBITOR E. I. DU PONT DE NEMOURS AND CO. (US) 1977-04-26 US claimed
US-3992395-A Process for the preparation of chlorinated phenylhydroxylamines RHONE-POULENC S.A. (FR) 1976-11-16 US claimed