Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.58 |
| ▸ | GSK3B | P49841 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.55 |
| ▸ | FEN1 | P39748 | 1/20 | 0.55 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22313390 | 0.88 | CES1 (0.56) | SMN1; SMN2MAPTL3MBTL1PTPN1GSK3B | |
| SCHEMBL136826 | 0.88 | CES1 (0.56) | SMN1; SMN2MAPTL3MBTL1PTPN1GSK3B | |
| SCHEMBL11332901 | 0.86 | CES1 (0.54) | SMN1; SMN2MAPTL3MBTL1PTPN1GSK3B | |
| Fluoride SCHEMBL28163020 | 0.86 | CES1 (0.54) | SMN1; SMN2MAPTL3MBTL1PTPN1GSK3B | |
| SCHEMBL6752860 | 0.86 | CES1 (0.54) | SMN1; SMN2MAPTL3MBTL1PTPN1GSK3B | |
| SCHEMBL395103 | 0.85 | GSK3B (0.48) | SMN1; SMN2MAPTL3MBTL1PTPN1GSK3B | |
| SCHEMBL26722630 | 0.84 | ERCC5 (0.58) | SMN1; SMN2GSK3BERCC5FEN1ALDH1A1 | |
| SCHEMBL14918493 | 0.82 | TSHR (0.52) | SMN1; SMN2GSK3BALDH1A1SRD5A2 | |
| SCHEMBL28568410 | 0.81 | HDAC1 (0.49) | SMN1; SMN2MAPTGSK3BLMNACYP1A2 | |
| SCHEMBL8287338 | 0.81 | ESR2 (0.57) | MAPTL3MBTL1RAB9AFFAR1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023210772-A1 | PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, PHOTOSENSOR, AND COMPOUND | 富士フイルム株式会社 | 2023-11-02 | — | — | WO | disclosed |
| CN-110272400-B | Synthesis method of 2-trifluoromethyl substituted furan compound and derivative thereof | 福州大学 | 2022-08-23 | — | — | CN | disclosed |
| CN-112679381-A | Method for synthesizing beta-ketonitrile and derivative thereof | 温州医科大学 | 2021-04-20 | — | — | CN | disclosed |
| EP-2069351-B1 | PYRAZOLOQUINAZOLINONES AS PARP INHIBITORS | ABBVIE INC (US) | 2015-10-28 | — | — | EP | disclosed |
| US-8183250-B2 | Potent PARP inhibitors | ABBOTT LABORATORIES (US) | 2012-05-22 | — | — | US | disclosed |
| US-20100063065-A1 | THIOPHENE DERIVATIVES AS PPAR AGONISTS I | INPHARMATICA LIMITED (GB) | 2010-03-11 | — | — | US | disclosed |
| US-20090298858-A1 | POTENT PARP INHIBITORS | ABBOTT LABORATORIES (US) | 2009-12-03 | — | — | US | disclosed |
| US-7625932-B2 | Pyrrole and pyrazole derivatives as potentiators of glutamate receptors | ELI LILLY AND COMPANY (US) | 2009-12-01 | — | — | US | disclosed |
| US-7625932-B2 | Pyrrole and pyrazole derivatives as potentiators of glutamate receptors | ELI LILLY AND COMPANY (US) | 2009-12-01 | — | — | US | disclosed |
| EP-2069351-A2 | PYRAZOLOQUINAZOLINONES AS PARP INHIBITORS | Abbott Laboratories (US) | 2009-06-17 | — | — | EP | disclosed |
| WO-2005044785-A1 | ARALKYL AMINES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2005-05-19 | — | — | WO | disclosed |
| WO-2005040110-A1 | PYRROLE AND PYRAZOLE DERIVATIVES AS POTENTIATORS OF GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 2005-05-06 | — | — | WO | disclosed |
| US-20040180948-A1 | 2-Amino-3-aroyl-4,5 alkylthiophenes: agonist allosteric enhancers at human A1 adenosine receptors | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-09-16 | — | — | US | disclosed |
| US-6713638-B2 | TREATING ISCHEMIC DISEASE, CARDIAC ARRHYTHMIAS, CHRONIC PAIN, INDUCING SLEEP IN A MAMMAL | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-03-30 | — | — | US | disclosed |
| US-20030078248-A1 | 2-amino-3-aroyl-4,5 alkylthiophenes: agonist allosteric enhancers at human A1 adenosine receptors | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-04-24 | — | — | US | disclosed |
| US-6323214-B1 | CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS AND ANALGESICS | MEDCO RESEARCH, INC | 2001-11-27 | — | — | US | disclosed |
| EP-1025106-A2 | ALLOSTERIC ADENOSINE RECEPTOR MODULATORS | Medco Research, Inc. (US) | 2000-08-09 | — | — | EP | disclosed |
| WO-1999021617-A2 | ALLOSTERIC ADENOSINE RECEPTOR MODULATORS | MEDCO RESEARCH, INC. (US) | 1999-05-06 | — | — | WO | disclosed |
| US-4420552-A | Method of producing printed images with a color facsimile printing device | Peck, Richard M. (US) | 1983-12-13 | — | — | US | disclosed |
| US-4390614-A | Color facsimile printing device comprising photosensitive ink in pores | Peck, Richard M. (US) | 1983-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298858-A1 | POTENT PARP INHIBITORS | PARP1, PARP2, PARP3 | SMN1; SMN2 2135/4885MAPT 2627/4885L3MBTL1 2650/4885 |
| US-20030078248-A1 | 2-amino-3-aroyl-4,5 alkylthiophenes: agonist allosteric enhancers at human A1 adenosine receptors | ADORA1, ADORA2A, ADORA3 | SMN1; SMN2 3809/4885MAPT 4206/4885L3MBTL1 1943/4885 |
| US-20040180948-A1 | 2-Amino-3-aroyl-4,5 alkylthiophenes: agonist allosteric enhancers at human A1 adenosine receptors | ADORA1, ADORA2A, ADORA3 | SMN1; SMN2 3809/4885MAPT 4206/4885L3MBTL1 1943/4885 |
| US-20100063065-A1 | THIOPHENE DERIVATIVES AS PPAR AGONISTS I | PPARG, PPARD, PPARA | SMN1; SMN2 3550/4885MAPT 4061/4885L3MBTL1 1021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.