Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | GSK3B | P49841 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22313390 | 0.98 | CES1 (0.56) | CES1MAPK1MAPTTDP1MEN1 | |
| SCHEMBL136826 | 0.98 | CES1 (0.56) | CES1MAPK1MAPTTDP1MEN1 | |
| SCHEMBL11332901 | 0.96 | CES1 (0.54) | CES1MAPK1MAPTTDP1MEN1 | |
| Fluoride SCHEMBL28163020 | 0.96 | CES1 (0.54) | CES1MAPK1MAPTTDP1MEN1 | |
| Formic Acid SCHEMBL28863403 | 0.90 | MAPK1 (0.48) | CES1MAPK1MAPTTDP1MEN1 | |
| SCHEMBL395103 | 0.86 | GSK3B (0.48) | CES1MAPK1MAPTTDP1MEN1 | |
| SCHEMBL3588115 | 0.86 | SMN1; SMN2 (0.58) | MAPTHPGDKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL11647086 | 0.85 | SMN1; SMN2 (0.44) | CES1MAPK1MAPTTDP1MEN1 | |
| Acetic Acid SCHEMBL28241860 | 0.84 | KMT2A (0.42) | CES1MAPK1MAPTTDP1MEN1 | |
| SCHEMBL397191 | 0.83 | GSK3B (0.50) | CES1MAPK1MAPTTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6706748-B2 | USE AS MICROBICIDES | NIHON BAYER AGROCHEM, K.K. (JP) | 2004-03-16 | — | — | US | disclosed |
| US-20030220197-A1 | Isothiazole derivatives | NIHON BAYER AGROCHEM K.K. (JP) | 2003-11-27 | — | — | US | disclosed |
| EP-1284970-A2 | ISOTHIAZOLE DERIVATIVES AND THEIR USE AS MICROBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 2003-02-26 | — | — | EP | disclosed |
| WO-2001077090-A2 | ISOTHIAZOLE DERIVATIVES AND THEIR USE AS MICROBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 2001-10-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220197-A1 | Isothiazole derivatives | IRF3, MSR1, ARG1 | CES1 391/4885MAPK1 3202/4885MAPT 4221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.