SCHEMBL3588966

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3588969	1.00	PDE9A (0.53)	PDE9APDE5AHDAC1HDAC8ADORA3
	SCHEMBL3587689	0.92	PDE9A (0.53)	PDE9APDE5AHDAC1HDAC8ADORA3
	SCHEMBL3587696	0.92	PDE9A (0.53)	PDE9APDE5AHDAC1HDAC8ADORA3
	SCHEMBL3597932	0.89	PDE9A (0.59)	PDE9APDE5AHDAC1HDAC8AURKA
	SCHEMBL11997358	0.89	PDE9A (0.55)	PDE9APDE5AHDAC1HDAC8ALDH1A1
	SCHEMBL3600478	0.89	PDE9A (0.52)	PDE9APDE5AHDAC1HDAC8AURKA
	SCHEMBL3600484	0.89	PDE9A (0.52)	PDE9APDE5AHDAC1HDAC8AURKA
	SCHEMBL3597938	0.89	PDE9A (0.59)	PDE9APDE5AHDAC1HDAC8AURKA
	SCHEMBL16226342	0.84	PDE9A (0.54)	PDE9APDE5AAURKAJAK2JAK1
	SCHEMBL3592634	0.82	PDE9A (0.57)	PDE9APDE5AAURKAJAK2JAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.