SCHEMBL358933

SCHEMBL358933

Nc1cc(Cl)ccc1-c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
HSD17B10 Q99714 3/20 0.54
CYP3A4 P08684 4/20 0.50
TSHR P16473 4/20 0.50
SMN1; SMN2 Q16637 4/20 0.50
ALOX15 P16050 2/20 0.50
TDP1 Q9NUW8 1/20 0.50
CYP1A2 P05177 2/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
TP53 P04637 2/20 0.48
MAP4K4 O95819 1/20 0.47
HPGD P15428 2/20 0.45
ALOX12 P18054 1/20 0.45
MAPK1 P28482 1/20 0.45
CSNK2A1 P68400 2/20 0.44
KMT2A Q03164 2/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
GFER P55789 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Alcohol SCHEMBL28859435 0.94 ALDH1A1 (0.48) ALDH1A1HSD17B10CYP3A4TSHRSMN1; SMN2
Toluene SCHEMBL28789748 0.91 CYP3A4 (0.47) ALDH1A1HSD17B10CYP3A4TSHRSMN1; SMN2
SCHEMBL21933896 0.90 ALDH1A1 (0.48) ALDH1A1HSD17B10CYP3A4TSHRSMN1; SMN2
SCHEMBL14906969 0.89 ALDH1A1 (0.56) ALDH1A1HSD17B10CYP3A4TSHRSMN1; SMN2
SCHEMBL17035151 0.88 ALDH1A1 (0.43) ALDH1A1HSD17B10CYP3A4TSHRSMN1; SMN2
SCHEMBL1824521 0.83 ALDH1A1 (0.54) ALDH1A1HSD17B10CYP3A4TSHRSMN1; SMN2
SCHEMBL30839712 0.81 ALDH1A1 (0.65) ALDH1A1HSD17B10CYP3A4TSHRSMN1; SMN2
SCHEMBL27185985 0.81 ALDH1A1 (0.65) ALDH1A1HSD17B10CYP3A4TSHRSMN1; SMN2
SCHEMBL30839752 0.81 ALDH1A1 (0.65) ALDH1A1HSD17B10CYP3A4TSHRSMN1; SMN2
Hydrochloric Acid SCHEMBL27976417 0.81 ALDH1A1 (0.52) ALDH1A1HSD17B10CYP3A4TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-222829484-U Synthetic structure of 4-chloro-2-aminobiphenyl stirrer 恒升德康(南京)医药科技有限公司 2025-05-06 CN claimed
CN-222623707-U 4-Chloro-2-aminobiphenyl extraction device 恒升德康(南京)医药科技有限公司 2025-03-18 CN claimed
CN-117903168-A Pyrrolo [2,3-d ] thiazole derivatives, and preparation method and application thereof 南开大学 2024-04-19 CN claimed
CN-113880759-B Preparation method of boscalid 江苏七洲绿色科技研究院有限公司 2023-09-05 CN claimed
CN-116640064-A Synthesis method of 4' -chloro-2-aminobiphenyl 山东京博农化科技股份有限公司 2023-08-25 CN claimed
CN-113831280-B Preparation method of boscalid 上海埃农生物科技有限公司 2023-08-15 CN claimed
CN-109563023-B Process for preparing substituted biphenyls 巴斯夫欧洲公司 2022-10-28 CN claimed
CN-111039860-B Synthetic method and application of 2-hydroxy-N- (4' -chlorobiphenyl-2-yl) nicotinamide 河北科技大学 2022-09-13 CN claimed
CN-113880759-A Preparation method of boscalid 江苏七洲绿色科技研究院有限公司 2022-01-04 CN claimed
CN-213853210-U 4-chlorine-2-aminobiphenyl extraction device 滕州市悟通香料有限责任公司 2021-08-03 CN claimed
CN-106883130-B A method of preparing halogenated biphenyl amine 泰州百力化学股份有限公司 2018-12-11 CN claimed
CN-106518793-B A kind of amides compound of the triazole ring containing 1,2,3- and the preparation method and application thereof 中国农业大学 2018-11-27 CN claimed
CN-108218716-A It is a kind of to prepare 4 '-methods of chloro- 2- aminobphenyls 江苏澄扬作物科技有限公司 2018-06-29 CN claimed
CN-108033908-A A kind of synthetic method of the chloro- N`- of 2- (4`- chlordiphenyl -2- bases) niacinamide 西安近代化学研究所 2018-05-15 CN claimed
EP-2593457-B1 PYRAZOLO[1,5A]PYRIMIDINE AND THIENO[3,2B]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS HOFFMANN LA ROCHE (CH) 2017-08-23 EP claimed
CN-106883130-A A kind of method for preparing halogenated biphenyl amine 泰州百力化学股份有限公司 2017-06-23 CN claimed
CN-106614786-A Preparation method of fungicide composition for melon and fruit cultivation 东莞市联洲知识产权运营管理有限公司 2017-05-10 CN claimed
CN-106518793-A 1,2,3-triazole-ring-containing amide compounds, and preparation method and application thereof 中国农业大学 2017-03-22 CN claimed
CN-104478797-A Preparation method of nicotinamide fungicide namely boscalid SUZHOU TOKIND CHEMICAL CO LTD 2015-04-01 CN claimed
EP-1252140-B1 PYRROLECARBOXAMIDES AND PYRROLETHIOAMIDES AS FUNGICIDES SYNGENTA PARTICIPATIONS AG (CH) 2009-05-13 EP claimed