SCHEMBL30839752

SCHEMBL30839752

Nc1cc(Cl)ccc1-c1ccc(Cl)cc1N

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.65
CYP3A4 P08684 4/20 0.65
TSHR P16473 3/20 0.65
SMN1; SMN2 Q16637 3/20 0.65
ALOX15 P16050 2/20 0.65
TDP1 Q9NUW8 1/20 0.65
TP53 P04637 1/20 0.62
HPGD P15428 2/20 0.56
ALOX12 P18054 1/20 0.56
MAPK1 P28482 1/20 0.56
HSD17B10 Q99714 1/20 0.56
KMT2A Q03164 3/20 0.48
GAA P10253 2/20 0.48
KDM4E B2RXH2 3/20 0.47
LMNA P02545 1/20 0.47
HTT P42858 1/20 0.47
S100A4 P26447 1/20 0.46
MGAM O43451 1/20 0.45
SI P14410 1/20 0.45
RAB9A P51151 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27185985 1.00 ALDH1A1 (0.65) ALDH1A1CYP3A4TSHRSMN1; SMN2ALOX15
SCHEMBL30839712 1.00 ALDH1A1 (0.65) ALDH1A1CYP3A4TSHRSMN1; SMN2ALOX15
SCHEMBL11214035 0.90 TSHR (0.58) ALDH1A1CYP3A4TSHRSMN1; SMN2ALOX15
SCHEMBL14906969 0.87 ALDH1A1 (0.56) ALDH1A1CYP3A4TSHRSMN1; SMN2ALOX15
SCHEMBL22884435 0.86 ALDH1A1 (0.50) ALDH1A1CYP3A4TSHRSMN1; SMN2ALOX15
SCHEMBL358933 0.81 ALDH1A1 (0.54) ALDH1A1CYP3A4TSHRSMN1; SMN2ALOX15
SCHEMBL17868056 0.81 ALDH1A1 (0.48) ALDH1A1CYP3A4TSHRSMN1; SMN2ALOX15
SCHEMBL21933896 0.81 ALDH1A1 (0.48) ALDH1A1CYP3A4TSHRSMN1; SMN2ALOX15
SCHEMBL16121126 0.81 HSD11B1 (0.50) ALDH1A1CYP3A4TSHRSMN1; SMN2ALOX15
SCHEMBL2500855 0.81 TSHR (0.48) ALDH1A1CYP3A4TSHRSMN1; SMN2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4594381-A1 NOVEL POLYURETHANE OR POLYURETHANE-UREA COMPOSITION WITH ENHANCED LOW TEMPERATURE PERFORMANCE Ingevity UK Ltd (GB) 2025-08-06 EP claimed
CN-120092033-A Novel polyurethane or polyurethane-urea compositions with enhanced low temperature properties 英格维蒂英国有限公司 2025-06-03 CN claimed
WO-2024068129-A1 NOVEL POLYURETHANE OR POLYURETHANE-UREA COMPOSITION WITH ENHANCED LOW TEMPERATURE PERFORMANCE INGEVITY UK LTD. (GB) 2024-04-04 WO claimed
EP-4594381-A1 NOVEL POLYURETHANE OR POLYURETHANE-UREA COMPOSITION WITH ENHANCED LOW TEMPERATURE PERFORMANCE Ingevity UK Ltd (GB) 2025-08-06 EP disclosed
WO-2024068129-A1 NOVEL POLYURETHANE OR POLYURETHANE-UREA COMPOSITION WITH ENHANCED LOW TEMPERATURE PERFORMANCE INGEVITY UK LTD. (GB) 2024-04-04 WO disclosed