SCHEMBL3589380

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3582701	0.81	TTR (0.58)	TTRGPR35KDM4EMEN1ALDH1A1
	SCHEMBL3580412	0.81	TTR (0.55)	TTRGPR35KDM4EMEN1ALDH1A1
	SCHEMBL1446704	0.80	TTR (0.53)	TTRGPR35KDM4EMEN1ALDH1A1
	SCHEMBL7370239	0.78	TTR (0.72)	TTRGPR35KDM4EMEN1ALDH1A1
	SCHEMBL3580478	0.77	TTR (0.58)	TTRGPR35KDM4EMEN1ALDH1A1
	SCHEMBL3592603	0.76	TTR (0.51)	TTRGPR35KDM4EMEN1ALDH1A1
	SCHEMBL3590402	0.76	FTO (0.60)	GPR35MEN1ALDH1A1MAPTCYP2C9
	SCHEMBL3590405	0.76	FTO (0.60)	GPR35MEN1ALDH1A1MAPTCYP2C9
	SCHEMBL28058774	0.75	TTR (0.41)	TTRGPR35KDM4EMEN1ALDH1A1
	SCHEMBL27743600	0.75	ASPH (0.43)	KDM4EMEN1ALDH1A1MAPTCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.