Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 10/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3581065 | 0.82 | PIK3CD (0.36) | — | |
| SCHEMBL3580556 | 0.78 | ABL1 (0.39) | OPRL1OPRM1OPRK1 | |
| SCHEMBL3590707 | 0.78 | ABL1 (0.39) | OPRL1OPRM1OPRK1 | |
| SCHEMBL3592265 | 0.78 | ABL1 (0.39) | OPRL1OPRM1OPRK1 | |
| SCHEMBL1354003 | 0.74 | OPRL1 (0.39) | OPRL1OPRM1OPRK1HTR1ADRD2 | |
| SCHEMBL1355216 | 0.74 | CYP19A1 (0.38) | DRD2 | |
| SCHEMBL1355225 | 0.73 | AURKA (0.41) | — | |
| SCHEMBL1355964 | 0.72 | OPRL1 (0.38) | OPRL1OPRM1OPRK1HTR1ADRD2 | |
| SCHEMBL3589173 | 0.69 | GSK3B (0.43) | — | |
| SCHEMBL3588605 | 0.69 | GSK3B (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100190787-A1 | Modulators of Mitotic Kinases | BIOGEN IDEC MA INC | 2010-07-29 | — | — | US | claimed |
| US-20100190787-A1 | Modulators of Mitotic Kinases | BIOGEN IDEC MA INC | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190787-A1 | Modulators of Mitotic Kinases | CDK1, BUB1, BUB1B | OPRL1 2638/4885OPRM1 1273/4885OPRK1 1095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.