Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 8/20 | 0.49 |
| ▸ | MPC2 | O95563 | 2/20 | 0.49 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3594379 | 0.87 | PPARG (0.48) | PTPN1CA2PPARGMPC2CYP2C8 | |
| SCHEMBL3589923 | 0.86 | ALDH1A1 (0.56) | PTPN1CA2PPARGMPC2CYP2C8 | |
| SCHEMBL525525 | 0.84 | PPARG (0.59) | PPARGMPC2CYP2C8CYP2C9FFAR1 | |
| SCHEMBL8182679 | 0.84 | PTPN1 (0.79) | PTPN1CA2PPARGMPC2CYP2C8 | |
| SCHEMBL3585109 | 0.83 | PPARG (0.45) | PTPN1PPARGMPC2CYP2C8CYP2C9 | |
| SCHEMBL6232223 | 0.83 | PTPN1 (0.61) | PTPN1CA2PPARGMPC2CYP2C8 | |
| SCHEMBL3583787 | 0.83 | PPARG (0.58) | PPARGMPC2CYP2C8CYP2C9FFAR1 | |
| SCHEMBL13866914 | 0.82 | PTPN1 (0.56) | PTPN1CA2PPARGMPC2CYP2C8 | |
| Hydrochloric Acid SCHEMBL3867515 | 0.81 | PTPN1 (0.55) | PTPN1CA2PPARGMPC2CYP2C8 | |
| SCHEMBL13875929 | 0.81 | PTPN1 (0.55) | PTPN1CA2PPARGMPC2CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004185-B1 | NOVEL HETEROCYCLIC DIPHENYL ETHERS | BEXEL PHARMACEUTICALS INC (US) | 2013-06-26 | — | — | EP | claimed |
| US-7781464-B2 | Heterocyclic diphenyl ethers | BEXEL PHARMACEUTICALS, INC. (US) | 2010-08-24 | — | — | US | claimed |
| US-20060247285-A1 | Novel heterocyclic diphenyl ethers | BEXEL PHARMACEUTICALS, INC. | 2006-11-02 | — | — | US | claimed |
| EP-2004185-B1 | NOVEL HETEROCYCLIC DIPHENYL ETHERS | BEXEL PHARMACEUTICALS INC (US) | 2013-06-26 | — | — | EP | disclosed |
| US-7781464-B2 | Heterocyclic diphenyl ethers | BEXEL PHARMACEUTICALS, INC. (US) | 2010-08-24 | — | — | US | disclosed |
| EP-2004185-A2 | NOVEL HETEROCYCLIC DIPHENYL ETHERS | Bexel Pharmaceuticals Inc (US) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007097992-A2 | NOVEL HETEROCYCLIC DIPHENYL ETHERS | BEXEL PHARMACEUTICALS, INC. (US) | 2007-08-30 | — | — | WO | disclosed |
| US-20060247285-A1 | Novel heterocyclic diphenyl ethers | BEXEL PHARMACEUTICALS, INC. | 2006-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247285-A1 | Novel heterocyclic diphenyl ethers | FFAR4, FFAR3, GPR119 | PTPN1 589/4885CA2 3652/4885PPARG 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.