Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3BCHECHRM1CHRM2CHRM3CHRM4CHRNA3CHRNA4CHRNB2CHRNB4ESR1ESR2GABRA1GABRB1GABRG2GBA1GHSRHRH1HTR1DHTR2AMAOBOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8UGCGrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL10955358 | 0.93 | CA4 (0.47) | TSHRLMNACA4CYP3A4TDP1 | |
| Cadaverine Tartrate SCHEMBL6048226 | 0.93 | LMNA (0.46) | TSHRLMNACA4CYP3A4TDP1 | |
| Cadaverine Tartrate SCHEMBL223358 | 0.92 | TSHR (0.47) | TSHRLMNACA4CYP3A4TDP1 | |
| Cadaverine Tartrate SCHEMBL372570 | 0.92 | TSHR (0.47) | TSHRLMNACA4CYP3A4TDP1 | |
| Cadaverine Tartrate SCHEMBL813951 | 0.92 | TSHR (0.47) | TSHRLMNACA4CYP3A4TDP1 | |
| Cadaverine Tartrate SCHEMBL23855755 | 0.92 | TSHR (0.47) | TSHRLMNACA4CYP3A4TDP1 | |
| Cadaverine Tartrate SCHEMBL6355357 | 0.92 | TSHR (0.47) | TSHRLMNACA4CYP3A4TDP1 | |
| Cadaverine Tartrate SCHEMBL119095 | 0.92 | TSHR (0.47) | TSHRLMNACA4CYP3A4TDP1 | |
| Cadaverine Tartrate SCHEMBL16527654 | 0.92 | TSHR (0.47) | TSHRLMNACA4CYP3A4TDP1 | |
| Cadaverine Tartrate SCHEMBL1985645 | 0.92 | TSHR (0.47) | TSHRLMNACA4CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100113260-A1 | Ruthenium compositions and methods of making the same | SYMYX TECHNOLOGIES, INC. (US) | 2010-05-06 | — | — | US | disclosed |
| US-20090286678-A1 | High Surface Area Metal And Metal Oxide Materials and Methods of Making the Same | SYMYX TECHNOLOGIES, INC. (US) | 2009-11-19 | — | — | US | disclosed |
| US-20090270251-A1 | Cobalt compositions and methods of making the same | SYMYX TECHNOLOGIES, INC. (US) | 2009-10-29 | — | — | US | disclosed |
| US-20090215613-A1 | Yttrium Compositions And Methods of Making the Same | SYMYX TECHNOLOGIES, INC. (US) | 2009-08-27 | — | — | US | disclosed |
| US-20090187036-A1 | Nickel Compositions And Methods of Making the Same | SYMYX TECHNOLOGIES, INC. (US) | 2009-07-23 | — | — | US | disclosed |
| US-20090182160-A1 | Vanadium Compositions And Methods of Making the Same | SYMYX TECHNOLOGIES, INC. (US) | 2009-07-16 | — | — | US | disclosed |
| US-20090029852-A1 | Molybdenum Compositions And Methods of Making the Same | FREESLATE, INC. | 2009-01-29 | — | — | US | disclosed |
| US-20090011930-A1 | Cerium Compositions and Methods of Making the Same | SYMYX TECHNOLOGIES, INC. (US) | 2009-01-08 | — | — | US | disclosed |
| EP-1879833-A2 | HIGH SURFACE AREA METAL AND METAL OXIDE MATERIALS AND METHODS OF MAKING SAME | Symyx Technologies, Inc. (US) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006119311-A2 | HIGH SURFACE AREA METAL AND METAL OXIDE MATERIALS AND METHODS OF MAKING SAME | SYMYX TECHNOLOGIES, INC. (US) | 2006-11-09 | — | — | WO | disclosed |
| US-4320091-A | SEPARATION OF DILVENT FROM FIRST STAGE-PRODUCT SATURATED DINITRIES; BY-PRODUCT INHIBITION | PHILLIPS PETROLEUM COMPANY (US) | 1982-03-16 | — | — | US | disclosed |
| US-4263228-A | Two stage catalytic hydrogenation of olefinically unsaturated dinitriles | PHILLIPS PETROLEUM COMPANY (US) | 1981-04-21 | — | — | US | disclosed |