Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 10/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.35 |
| ▸ | CNR1 | P21554 | 3/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BRD2 | P25440 | 1/20 | 0.32 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.32 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.32 |
| ▸ | ACP1 | P24666 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3088975 | 0.91 | DPP4 (0.40) | DPP4DPP8CNR1BRD4BRD2 | |
| SCHEMBL3259669 | 0.83 | CNR1 (0.35) | DPP4DPP8CNR1BRD4BRD2 | |
| SCHEMBL13316370 | 0.81 | DPP4 (0.41) | DPP4DPP8ACP1 | |
| SCHEMBL3084453 | 0.80 | CNR1 (0.45) | DPP4DPP8CNR1 | |
| SCHEMBL3087663 | 0.78 | CNR1 (0.47) | DPP4DPP8CNR1 | |
| SCHEMBL3595741 | 0.76 | DPP4 (0.44) | DPP4DPP8CNR1 | |
| SCHEMBL3604583 | 0.76 | CNR1 (0.41) | DPP4DPP8CNR1 | |
| SCHEMBL3087445 | 0.75 | DPP4 (0.37) | DPP4BRD4BRD2BRD3BRDT | |
| SCHEMBL3089159 | 0.75 | CNR1 (0.40) | DPP4DPP8CNR1 | |
| SCHEMBL3089834 | 0.74 | CNR1 (0.43) | DPP4DPP8CNR1ACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728146-B2 | Enzyme inhibitors | PROBIODRUG AG (DE) | 2010-06-01 | — | — | US | claimed |