Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 10/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | MDM4 | O15151 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3091375 | 0.92 | DPP4 (0.47) | DPP4DPP8NSD2MDM4TP53 | |
| SCHEMBL3600269 | 0.90 | DPP4 (0.41) | DPP4DPP8NSD2CYP3A4CXCR2 | |
| SCHEMBL3091436 | 0.88 | DPP4 (0.46) | DPP4DPP8NSD2CYP3A4KCNH2 | |
| SCHEMBL3102277 | 0.88 | DPP4 (0.44) | DPP4DPP8NSD2MDM4TP53 | |
| SCHEMBL3096840 | 0.88 | DPP4 (0.46) | DPP4DPP8PKMMDM4TP53 | |
| SCHEMBL3079559 | 0.88 | DPP4 (0.51) | DPP4DPP8MDM4TP53MDM2 | |
| SCHEMBL3606001 | 0.86 | DPP4 (0.44) | DPP4DPP8CYP3A4DPP9 | |
| SCHEMBL13316370 | 0.86 | DPP4 (0.41) | DPP4DPP8CYP3A4 | |
| SCHEMBL3089796 | 0.86 | DPP4 (0.44) | DPP4DPP8MDM4MDM2CNR1 | |
| SCHEMBL3595249 | 0.86 | DPP4 (0.47) | DPP4DPP8NSD2MDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728146-B2 | Enzyme inhibitors | PROBIODRUG AG (DE) | 2010-06-01 | — | — | US | claimed |