Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.40 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 5/20 | 0.40 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3092513 | 0.90 | DPP4 (0.47) | CNR1KDM4CKDM2BDPP4DPP8 | |
| SCHEMBL3586450 | 0.85 | TAAR1 (0.42) | CNR1KDM4CDPP4DPP8TAAR1 | |
| SCHEMBL3604409 | 0.83 | DPP4 (0.45) | CNR1KDM4CDPP4DPP8TAAR1 | |
| SCHEMBL3596995 | 0.82 | SLC6A4 (0.41) | DPP4DPP8 | |
| SCHEMBL3096850 | 0.82 | DPP4 (0.44) | DPP4DPP8CYP3A4 | |
| SCHEMBL3599723 | 0.79 | CNR1 (0.42) | CNR1KDM4CKDM2BDPP4DPP8 | |
| SCHEMBL3084580 | 0.78 | DPP4 (0.49) | CNR1DPP4DPP8CYP3A4 | |
| SCHEMBL3600855 | 0.78 | DPP4 (0.45) | KDM4CDPP4DPP8CYP3A4 | |
| SCHEMBL3596861 | 0.78 | TAAR1 (0.47) | CNR1DPP4DPP8TAAR1 | |
| SCHEMBL3604955 | 0.77 | DPP4 (0.48) | CNR1DPP4DPP8CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728146-B2 | Enzyme inhibitors | PROBIODRUG AG (DE) | 2010-06-01 | — | — | US | claimed |