SCHEMBL3591759

SCHEMBL3591759

COC(=O)NC/C=C/c1c[nH]c(=N)s1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13909655 0.84
SCHEMBL28625222 0.65 MAOB (0.54)
SCHEMBL28629981 0.65 MAOB (0.54)
SCHEMBL3586295 0.62
SCHEMBL30993502 0.61 FPR3 (0.37)
SCHEMBL13036715 0.61 KCNA6 (0.61)
SCHEMBL27252612 0.60
SCHEMBL3586492 0.58 KCNA6 (0.34)
SCHEMBL4071211 0.57
SCHEMBL11542628 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7838681-B2 Synthesis of substituted heterocyclic compounds CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2010-11-23 US disclosed
US-7838681-B2 Synthesis of substituted heterocyclic compounds CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2010-11-23 US disclosed
EP-1620440-B1 SYNTHESIS OF SUBSTITUTED HETEROCYCLIC COMPOUNDS CENTRE NAT RECH SCIENT (FR) 2009-03-11 EP disclosed
US-20070106077-A1 Synthesis of substituted heterocyclic compounds UNIVERSITE DE PARIS SUD (FR) 2007-05-10 US disclosed
US-20070106077-A1 Synthesis of substituted heterocyclic compounds UNIVERSITE DE PARIS SUD (FR) 2007-05-10 US disclosed
US-20070106077-A1 Synthesis of substituted heterocyclic compounds UNIVERSITE DE PARIS SUD (FR) 2007-05-10 US disclosed
WO-2004101573-A9 SYNTHESIS OF SUBSTITUTED HETEROCYCLIC COMPOUNDS CENTRE NAT RECH SCIENT (FR) 2005-01-06 WO disclosed