SCHEMBL359203

SCHEMBL359203

CN1CCC(NC(=O)OC(C)(C)C)CC1

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CTSK P43235 2/20 0.59
BTK Q06187 1/20 0.51
DRD2 P14416 3/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
KCNA3 P22001 1/20 0.50
HSD11B1 P28845 2/20 0.49
CYP2C9 P11712 1/20 0.49
EPHX1 P07099 2/20 0.49
NAMPT P43490 1/20 0.47
GAA P10253 1/20 0.46
CKS1B P61024 1/20 0.46
SKP1 P63208 1/20 0.46
SKP2 Q13309 1/20 0.46
KDM1A O60341 1/20 0.45
MAOB P27338 1/20 0.45
SSTR4 P31391 1/20 0.45
EPHX2 P34913 1/20 0.44
DRD3 P35462 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL8483326 0.95 CTSK (0.55) CTSKBTKDRD2CA1CA2
SCHEMBL17793196 0.94 CA1 (0.56) CTSKBTKDRD2CA1CA2
SCHEMBL16055278 0.91 CTSK (0.51) CTSKBTKDRD2CA1CA2
SCHEMBL21847055 0.90 DRD2 (0.52) CTSKBTKDRD2CA1CA2
SCHEMBL359644 0.90 CTSK (0.64) CTSKBTKDRD2CA1CA2
SCHEMBL428907 0.90 CTSK (0.64) CTSKBTKDRD2CA1CA2
SCHEMBL1959133 0.90 CTSK (0.64) CTSKBTKDRD2CA1CA2
Hydrochloric Acid SCHEMBL27630477 0.88 CTSK (0.62) CTSKBTKDRD2CA1CA2
Piperidine SCHEMBL27605900 0.88 CTSK (0.49) CTSKBTKDRD2CA1CA2
SCHEMBL24068416 0.86 CTSK (0.59) CTSKBTKDRD2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105829293-A Novel piperidine carboxamide compound, preparation method, and usage thereof 中国人民解放军军事医学科学院毒物药物研究所 2016-08-03 CN claimed
US-20260070917-A1 CYCLIN DEPENDENT KINASE DEGRADERS AND METHODS OF USE THEREOF DIFFERENTIATED THERAPEUTICS INC (US) 2026-03-12 US disclosed
CN-119013277-A TYK2 degrading agent and application thereof 凯麦拉医疗公司 2024-11-22 CN disclosed
CN-118302426-A Compounds and methods for modulating splicing 雷密克斯医疗公司 2024-07-05 CN disclosed
CN-118119609-A Imidazole derivatives and their use as antibiotics 豪夫迈·罗氏有限公司 2024-05-31 CN disclosed
CN-118076610-A Macrocyclic compounds with ENT1 inhibitory activity ITEOS比利时公司 2024-05-24 CN disclosed
CN-117957225-A Compounds for targeting degradation of IRAK4 proteins 渤健马萨诸塞州股份有限公司 2024-04-30 CN disclosed
CN-117940414-A Compounds for targeting IRAK4 protein degradation 渤健马萨诸塞州股份有限公司 2024-04-26 CN disclosed
CN-117916235-A Cyclin dependent kinase inhibitors 泰州亿腾景昂药业股份有限公司 2024-04-19 CN disclosed
CN-117715904-A CDK2 degrading agents and uses thereof 凯麦拉医疗公司 2024-03-15 CN disclosed
CN-1228083-A Arylsulfonylamino hydroxamic acid derivatives PFIZER (US) 1999-09-08 CN disclosed
CN-1223659-A Fused imidazopyridine derivatives as antihyperlipidemic agents TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1999-07-21 CN disclosed
EP-0922030-A1 ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES PFIZER INC. (US) 1999-06-16 EP disclosed
EP-0871628-A1 QUINOLIZINONE TYPE COMPOUNDS Abbott Laboratories (US) 1998-10-21 EP disclosed
US-5726182-A TREATMENT OF BACTERIAL INFECTIONS ABBOTT LABORATORIES (US) 1998-03-10 US disclosed
WO-1998007697-A1 ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES PFIZER INC. (US) 1998-02-26 WO disclosed
WO-1996039407-A1 QUINOLIZINONE TYPE COMPOUNDS ABBOTT LABORATORIES (US) 1996-12-12 WO disclosed
US-5580872-A ADMINISTERING IN THE TREATMENT OF BACTERIAL INFECTIONS ABBOTT LABORATORIES (US) 1996-12-03 US disclosed
EP-0723545-A1 QUINOLIZINONE TYPE COMPOUNDS ABBOTT LABORATORIES (US) 1996-07-31 EP disclosed
WO-1995010519-A1 QUINOLIZINONE TYPE COMPOUNDS ABBOTT LABORATORIES (US) 1995-04-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070917-A1 CYCLIN DEPENDENT KINASE DEGRADERS AND METHODS OF USE THEREOF CDK2, CCNK, CCNC CTSK 598/4885BTK 829/4885DRD2 3525/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.