Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 8/20 | 0.33 |
| ▸ | CPT2 | P23786 | 4/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | CPT1B | Q92523 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3593480 | 0.93 | CPT1A (0.35) | CPT1ACPT2KDM4EGABRA1GABRG2 | |
| SCHEMBL3576368 | 0.92 | KDM4E (0.35) | CPT1ACPT2GRIN1GRIN2BKDM4E | |
| Potassium Ion SCHEMBL3579672 | 0.92 | CPT1A (0.33) | CPT1ACPT2GRIN1GRIN2BKDM4E | |
| SCHEMBL3581098 | 0.92 | CPT1A (0.33) | CPT1ACPT2GRIN1GRIN2BKDM4E | |
| SCHEMBL3585326 | 0.88 | KDM4E (0.32) | CPT1ACPT2GRIN1GRIN2BKDM4E | |
| SCHEMBL3595199 | 0.88 | GRIN1 (0.34) | CPT1ACPT2GRIN1GRIN2BKDM4E | |
| SCHEMBL3575795 | 0.87 | RORC (0.35) | CPT1ACPT2GRIN1GRIN2BCPT1B | |
| SCHEMBL3576341 | 0.86 | PDE4B (0.34) | CPT1ACPT2KDM4EGABRA1GABRG2 | |
| SCHEMBL3581779 | 0.85 | TLR9 (0.34) | CPT1ACPT2GRIN2BGABRA1GABRG2 | |
| SCHEMBL3588046 | 0.85 | ALK (0.34) | CPT1ACPT2GRIN1GRIN2BGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286191-A1 | 2-Arylthiazole Derivatives as CXCR3 Receptor Modulators | MERCK SHARP & DOHME CORP. | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286191-A1 | 2-Arylthiazole Derivatives as CXCR3 Receptor Modulators | CXCR3, CXCR1, CXCR2 | CPT1A 1947/4885CPT2 2552/4885GRIN1 571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.