SCHEMBL3592989

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3599970	1.00	PDE9A (0.80)	PDE9APDE5AHPGDMEN1KMT2A
	SCHEMBL3593184	0.93	PDE9A (0.77)	PDE9APDE5AHPGDPLATSMN1; SMN2
	SCHEMBL3597128	0.93	PDE9A (0.75)	PDE9APDE5APLATLMNASMN1; SMN2
	SCHEMBL3601625	0.93	PDE9A (0.81)	PDE9APDE5AKMT2ALMNAPARP1
	SCHEMBL3599103	0.93	PDE9A (0.78)	PDE9APDE5AHPGDPLATSMN1; SMN2
	SCHEMBL3595105	0.89	PDE9A (0.79)	PDE9APDE5AKMT2APARP1SPR
	SCHEMBL3493337	0.89	PDE9A (1.00)	PDE9APDE5APARP1
	SCHEMBL3595262	0.89	PDE9A (0.70)	PDE9APDE5AHPGDPLATLMNA
	SCHEMBL3579453	0.88	PDE9A (0.78)	PDE9APDE5AMEN1KMT2ALMNA
	SCHEMBL3597945	0.86	PDE9A (0.75)	PDE9APDE5AHPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.