Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.37 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.37 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.37 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3586319 | 0.86 | ADORA2A (0.43) | CYP2C19ADORA2AADORA1ALDH1A1KDM4E | |
| SCHEMBL14390999 | 0.85 | ADORA1 (0.47) | CYP2C19ADORA2AADORA1ALDH1A1KDM4E | |
| SCHEMBL3635397 | 0.85 | KDM4E (0.44) | CYP2C19ACMSDADORA2AADORA1ALDH1A1 | |
| SCHEMBL3594245 | 0.84 | PDE5A (0.47) | CYP2C19ACMSDADORA2AADORA1ALDH1A1 | |
| SCHEMBL13545959 | 0.83 | ALDH1A1 (0.49) | ADORA2AADORA1ALDH1A1KDM4EHPGD | |
| SCHEMBL13545955 | 0.83 | ADORA2A (0.38) | CYP2C19ADORA2AADORA1ALDH1A1KDM4E | |
| SCHEMBL3599988 | 0.82 | ALDH1A1 (0.43) | ADORA2AADORA1ALDH1A1KDM4EHPGD | |
| SCHEMBL3588667 | 0.82 | KDM4E (0.45) | CYP2C19ADORA2AADORA1ALDH1A1KDM4E | |
| SCHEMBL13545960 | 0.80 | MAPT (0.48) | CYP2C19ADORA2AADORA1ALDH1A1KDM4E | |
| SCHEMBL3592409 | 0.79 | CYP2C19 (0.49) | CYP2C19ACMSDADORA2AADORA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100009973-A1 | Integrase Inhibitors 3 | AVEXA LIMITED (AU) | 2010-01-14 | — | — | US | disclosed |
| EP-2019827-A1 | INTEGRASE INHIBITORS 3 | Avexa Limited (AU) | 2009-02-04 | — | — | EP | disclosed |
| WO-2007124546-A1 | INTEGRASE INHIBITORS 3 | AVEXA LIMITED (AU) | 2007-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009973-A1 | Integrase Inhibitors 3 | TYMP, IMPDH1, IMPDH2 | CYP2C19 150/4885ACMSD 4770/4885ADORA2A 3605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.