⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL359551 | 1.00 | — | — | |
| SCHEMBL4478548 | 1.00 | — | — | |
| Thiophene SCHEMBL27562608 | 0.84 | RAB9A (0.33) | — | |
| SCHEMBL24056630 | 0.75 | — | — | |
| SCHEMBL28882647 | 0.73 | — | — | |
| SCHEMBL15866580 | 0.73 | — | — | |
| SCHEMBL5393184 | 0.71 | RAB9A (0.36) | — | |
| SCHEMBL22340623 | 0.71 | RAB9A (0.36) | — | |
| SCHEMBL8615913 | 0.71 | RAB9A (0.36) | — | |
| SCHEMBL5393178 | 0.71 | RAB9A (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304203-B | Method for recycling nitroguanidine acidic wastewater | 南京鹳山化工科技有限公司 | 2024-01-09 | — | — | CN | claimed |
| CN-115304203-A | Method for resource utilization of nitroguanidine acidic wastewater | 南京鹳山化工科技有限公司 | 2022-11-08 | — | — | CN | claimed |
| CN-115304203-B | Method for recycling nitroguanidine acidic wastewater | 南京鹳山化工科技有限公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-111655700-B | Oxadiazolopyridine derivatives as ghrelin O-acyltransferase (GOAT) inhibitors | 勃林格殷格翰国际有限公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-112851588-B | Micro-reaction system and method for continuously preparing 2-methyl-4-amino-5-cyanopyrimidine by using same | 复旦大学 | 2023-04-21 | — | — | CN | disclosed |
| CN-115304203-A | Method for resource utilization of nitroguanidine acidic wastewater | 南京鹳山化工科技有限公司 | 2022-11-08 | — | — | CN | disclosed |
| CN-111655700-A | Benzyl-, (pyridin-3-yl) methyl-or (pyridin-4-yl) methyl-substituted oxadiazolopyridine derivatives as ghrelin O-acyltransferase (GOAT) inhibitors | 勃林格殷格翰国际有限公司 | 2020-09-11 | — | — | CN | disclosed |
| US-20180298026-A1 | Pyrazolo[1,5a]Pyrimidine Derivatives as IRAK4 Modulators | HOFFMANN-LA ROCHE INC. | 2018-10-18 | — | — | US | disclosed |
| US-10023589-B2 | Pyrazolo[1,5a]pyrimidine derivatives as IRAK4 modulators | HOFFMANN-LA ROCHE INC. (US) | 2018-07-17 | — | — | US | disclosed |
| EP-3252054-A1 | PYRAZOLO[1,5A]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS | F. Hoffmann-La Roche AG (CH) | 2017-12-06 | — | — | EP | disclosed |
| EP-2593457-B1 | PYRAZOLO[1,5A]PYRIMIDINE AND THIENO[3,2B]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS | HOFFMANN LA ROCHE (CH) | 2017-08-23 | — | — | EP | disclosed |
| US-5478942-A | Antiinflammatory agents, antiagglomerants | KARL THOMAE GMBH (DE) | 1995-12-26 | — | — | US | disclosed |
| US-5276049-A | Treatment of thrombosis | DR. KARL THOMAE GMBH (DE) | 1994-01-04 | — | — | US | disclosed |
| EP-0503548-A1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-09-16 | — | — | EP | disclosed |
| EP-0151294-B1 | 2-SUBSTITUTED-6-(5-SUBSTITUTED-2-PYRIMIDINYL)NAPHTHALENES AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THE SAME | Chisso Corporation (JP) | 1988-06-22 | — | — | EP | disclosed |
| US-4585575-A | LIQUID CRYSTALS HAVING LARGE VALUE OF OPTICAL ANISOTROPY | CHISSO CORPORATION (JP) | 1986-04-29 | — | — | US | disclosed |
| EP-0151294-A1 | 2-Substituted-6-(5-substituted-2-pyrimidinyl)naphthalenes and liquid crystal compositions containing the same | Chisso Corporation (JP) | 1985-08-14 | — | — | EP | disclosed |
| US-4358393-A | MODULATORS FOR ELECTROOPTICAL APPARATUS; DISPLAYING; HIGH TEMPERATURE | VEB WERK FUR FERNSEHELEKTRONIK IM VEB KOMBINAT MIKROELEKTRONIK (DD) | 1982-11-09 | — | — | US | disclosed |
| US-3966791-A | Preparation of dialkyl amino acrylonitrile | HOFFMANN-LA ROCHE INC. (US) | 1976-06-29 | — | — | US | disclosed |
| US-3965141-A | Process for producing dialkyl aminoacrylonitrile | HOFFMANN-LA ROCHE INC. (US) | 1976-06-22 | — | — | US | disclosed |