Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22340623 | 1.00 | RAB9A (0.36) | RAB9AKMT2ASMN1; SMN2CYP2C9 | |
| SCHEMBL5393184 | 1.00 | RAB9A (0.36) | RAB9AKMT2ASMN1; SMN2CYP2C9 | |
| Perchlorate SCHEMBL4256245 | 0.92 | RAB9A (0.32) | RAB9AKMT2ASMN1; SMN2 | |
| Perchlorate SCHEMBL4256243 | 0.92 | RAB9A (0.32) | RAB9AKMT2ASMN1; SMN2 | |
| Oxalic Acid SCHEMBL22322845 | 0.86 | CYP2C9 (0.33) | RAB9ACYP2C9 | |
| SCHEMBL24056630 | 0.71 | — | — | |
| SCHEMBL359552 | 0.71 | — | — | |
| SCHEMBL359551 | 0.71 | — | — | |
| SCHEMBL4478548 | 0.71 | — | — | |
| SCHEMBL4256247 | 0.70 | CYP2C9 (0.30) | CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2754660-B1 | Pyridazinone derivatives | MERCK PATENT GMBH (DE) | 2016-11-02 | — | — | EP | disclosed |
| US-9284300-B2 | Pyridazinone derivatives | MERCK PATENT GMBH (DE) | 2016-03-15 | — | — | US | disclosed |
| US-20150011534-A1 | PYRIDAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2015-01-08 | — | — | US | disclosed |
| US-8927540-B2 | Pyridazinone derivatives | MERCK PATENT GMBH (DE) | 2015-01-06 | — | — | US | disclosed |
| US-8921357-B2 | Pyridazinone derivatives | MERCK PATENT GMBH (DE) | 2014-12-30 | — | — | US | disclosed |
| EP-2164843-B1 | PYRIDAZINONE DERIVATES | MERCK PATENT GMBH (DE) | 2014-10-29 | — | — | EP | disclosed |
| US-8580781-B2 | Pyridazinone derivatives | MERCK PATENT GMBH (DE) | 2013-11-12 | — | — | US | disclosed |
| US-20130184260-A1 | PYRIDAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2013-07-18 | — | — | US | disclosed |
| US-20130184261-A1 | PYRIDAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2013-07-18 | — | — | US | disclosed |
| US-20100234354-A1 | PYRIDAZINONE DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-09-16 | — | — | US | disclosed |
| WO-2009006959-A1 | PYRIDAZINONE DERIVATES | MERCK PATENT GMBH (DE) | 2009-01-15 | — | — | WO | disclosed |
| US-7172907-B2 | Cyanine dye labelling reagents with meso-substitution | GE HEALTHCARE BIO-SCIENCES CORP. (US) | 2007-02-06 | — | — | US | disclosed |
| US-20040186278-A1 | Cyanine dye labelling reagents with meso-substitution | GLOBAL LIFE SCIENCES SOLUTIONS USA LLC | 2004-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130184261-A1 | PYRIDAZINONE DERIVATIVES | MET, RET, ERBB2 | RAB9A 3369/4885KMT2A 904/4885SMN1; SMN2 3754/4885 |
| US-20040186278-A1 | Cyanine dye labelling reagents with meso-substitution | HCCS, CBR3, CYCS | RAB9A 2107/4885KMT2A 2010/4885SMN1; SMN2 4141/4885 |
| US-20130184260-A1 | PYRIDAZINONE DERIVATIVES | MET, RET, ERBB2 | RAB9A 3261/4885KMT2A 1033/4885SMN1; SMN2 3614/4885 |
| US-20150011534-A1 | PYRIDAZINONE DERIVATIVES | MET, RET, ERBB2 | RAB9A 3261/4885KMT2A 1033/4885SMN1; SMN2 3614/4885 |
| US-20100234354-A1 | PYRIDAZINONE DERIVATIVES | MET, RET, ERBB2 | RAB9A 3048/4885KMT2A 1065/4885SMN1; SMN2 3688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.