Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.43 |
| ▸ | MARS1 | P56192 | 2/20 | 0.40 |
| ▸ | CDC7 | O00311 | 2/20 | 0.40 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3091375 | 0.91 | DPP4 (0.47) | DPP4DPP8CYP3A4 | |
| SCHEMBL3079559 | 0.89 | DPP4 (0.51) | DPP4DPP8CYP3A4DPP9 | |
| SCHEMBL3084749 | 0.87 | P2RX7 (0.46) | DPP4DPP8MARS1CYP3A4DPP9 | |
| SCHEMBL3091436 | 0.86 | DPP4 (0.46) | DPP4DPP8CYP3A4DPP9 | |
| SCHEMBL3096840 | 0.86 | DPP4 (0.46) | DPP4DPP8CYP3A4DPP9 | |
| SCHEMBL3595741 | 0.86 | DPP4 (0.44) | DPP4DPP8CYP3A4DPP9 | |
| SCHEMBL3102277 | 0.86 | DPP4 (0.44) | DPP4DPP8 | |
| SCHEMBL3600164 | 0.86 | DPP4 (0.49) | DPP4DPP8 | |
| SCHEMBL3088192 | 0.85 | DPP4 (0.46) | DPP4DPP8CYP3A4 | |
| SCHEMBL3089796 | 0.84 | DPP4 (0.44) | DPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728146-B2 | Enzyme inhibitors | PROBIODRUG AG (DE) | 2010-06-01 | — | — | US | claimed |