Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.63 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.56 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TYR | P14679 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | BID | P55957 | 3/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.49 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.49 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL358692 | 1.00 | LIPG (0.63) | LIPGCYP4F2CYP4A11ALOX5MEN1 | |
| SCHEMBL477512 | 1.00 | LIPG (0.63) | LIPGCYP4F2CYP4A11ALOX5MEN1 | |
| SCHEMBL17027856 | 1.00 | LIPG (0.63) | LIPGCYP4F2CYP4A11ALOX5MEN1 | |
| SCHEMBL477547 | 1.00 | LIPG (0.63) | LIPGCYP4F2CYP4A11ALOX5MEN1 | |
| SCHEMBL17027765 | 1.00 | LIPG (0.63) | LIPGCYP4F2CYP4A11ALOX5MEN1 | |
| SCHEMBL359310 | 1.00 | LIPG (0.63) | LIPGCYP4F2CYP4A11ALOX5MEN1 | |
| SCHEMBL358878 | 1.00 | LIPG (0.63) | LIPGCYP4F2CYP4A11ALOX5MEN1 | |
| SCHEMBL359569 | 1.00 | LIPG (0.63) | LIPGCYP4F2CYP4A11ALOX5MEN1 | |
| Alcohol SCHEMBL9016688 | 0.98 | LIPG (0.61) | LIPGCYP4F2CYP4A11ALOX5MEN1 | |
| SCHEMBL28732571 | 0.98 | LIPG (0.61) | LIPGCYP4F2CYP4A11ALOX5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9758445-B2 | Preparation of surfactants via cross-metathesis | MATERIA, INC. (US) | 2017-09-12 | — | — | US | disclosed |
| US-20160186094-A1 | PREPARATION OF SURFACTANTS VIA CROSS-METATHESIS | MATERIA, INC. | 2016-06-30 | — | — | US | disclosed |
| WO-2015126462-A1 | PREPARATION OF SURFACTANTS VIA CROSS-METATHESIS | MATERIA, INC. (US) | 2015-08-27 | — | — | WO | disclosed |
| CN-102762532-B | The manufacture method of cyano group alkenyl cyclopropanecarboxylic acid salt | SUMITOMO CHEMICAL CO.,LTD. (JP) | 2015-07-29 | — | — | CN | disclosed |
| EP-1792889-B1 | Process for the preparation of carboxylic acid esters | SUMITOMO CHEMICAL CO (JP) | 2015-03-04 | — | — | EP | disclosed |
| CN-102365264-B | Process for producing 3-(2-cyano-1-propenyl)-2,2- dimethylcyclopropanecarboxylic acid or salt thereof | SUMITOMO CHEMICAL CO | 2014-05-21 | — | — | CN | disclosed |
| EP-1547995-B1 | Process for the preparation of carboxylic acid esters | SUMITOMO CHEMICAL CO (JP) | 2014-05-07 | — | — | EP | disclosed |
| EP-2418197-B1 | PROCESS FOR PRODUCING 3-(2-CYANO-1-PROPENYL)-2,2- DIMETHYLCYCLOPROPANECARBOXYLIC ACID OR SALT THEREOF | SUMITOMO CHEMICAL CO (JP) | 2014-05-07 | — | — | EP | disclosed |
| US-8563786-B2 | Method for producing optically active alcohol | MITSUI CHEMICALS, INC. (JP) | 2013-10-22 | — | — | US | disclosed |
| US-8461370-B2 | Process for producing 3-(2-cyano-1-propenyl)-2,2- dimethylcyclopropanecarboxylic acid or salt thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-06-11 | — | — | US | disclosed |
| EP-0992479-A1 | Method for producing cyclopropanecarboxylates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-04-12 | — | — | EP | disclosed |
| CN-1020594-C | PREPARATION OF PHENYL NONATETRAENOIC ACID DERIVS. | MOFFMANN LA ROCHE & CO AG F (CH) | 1993-05-12 | — | — | CN | disclosed |
| US-4894480-A | Phenyl substituted-2,4,6,8-nonatetraenoic acid | HOFFMANN-LA ROCHE INC. (US) | 1990-01-16 | — | — | US | disclosed |
| US-4883613-A | TREATMENT OF RHEUMATOID ARTHRITIS, IMMUNOSUPPRESSANTS | HOFFMANN-LA ROCHE INC. (US) | 1989-11-28 | — | — | US | disclosed |
| US-4883614-A | TREATMENT OF RHEUMATOID ARTHRITIS, IMMUNOSUPPRESSANTS | HOFFMAN-LA ROCHE INC. (US) | 1989-11-28 | — | — | US | disclosed |
| US-4780251-A | ANTIRHEUMATIC AGENTS, IMMUNOSUPPRESSANTS | HOFFMAN-LA ROCHE INC. (US) | 1988-10-25 | — | — | US | disclosed |
| EP-0169571-B1 | PHENYLNONATETRAENIC-ACID DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1988-03-09 | — | — | EP | disclosed |
| CN-85108591-A | Preparation of phenyl-nonatetraenoic acid derivatives | — | 1987-06-03 | — | — | CN | disclosed |
| US-4648996-A | ANTIRHEUMATIC AGENTS, IMMUNOSUPRESSANTS | HOFFMANN-LA ROCHE INC. (US) | 1987-03-10 | — | — | US | disclosed |
| EP-0169571-A1 | Phenylnonatetraenic-acid derivatives, their preparation and pharmaceutical compositions containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1986-01-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160186094-A1 | PREPARATION OF SURFACTANTS VIA CROSS-METATHESIS | SMURF2, EPHX2, SMURF1 | LIPG 1433/4885CYP4F2 849/4885CYP4A11 373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.