Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.40 |
| ▸ | MARS1 | P56192 | 1/20 | 0.39 |
| ▸ | HSD17B13 | Q7Z5P4 | 2/20 | 0.38 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3091375 | 0.86 | DPP4 (0.47) | DPP4DPP8NSD2 | |
| SCHEMBL3600164 | 0.86 | DPP4 (0.49) | DPP4DPP8 | |
| SCHEMBL3595932 | 0.86 | DPP4 (0.49) | DPP4DPP8 | |
| SCHEMBL3096840 | 0.84 | DPP4 (0.46) | DPP4DPP8 | |
| SCHEMBL3092340 | 0.82 | DPP4 (0.42) | DPP4DPP8HSD17B13GRIN2B | |
| SCHEMBL3089796 | 0.82 | DPP4 (0.44) | DPP4DPP8 | |
| SCHEMBL3091436 | 0.82 | DPP4 (0.46) | DPP4DPP8NSD2 | |
| SCHEMBL3102277 | 0.82 | DPP4 (0.44) | DPP4DPP8NSD2 | |
| SCHEMBL3595741 | 0.82 | DPP4 (0.44) | DPP4DPP8NSD2 | |
| SCHEMBL3079559 | 0.82 | DPP4 (0.51) | DPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728146-B2 | Enzyme inhibitors | PROBIODRUG AG (DE) | 2010-06-01 | — | — | US | claimed |