Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 5/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.73 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.56 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.56 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.50 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3597216 | 1.00 | ALDH1A1 (1.00) | ALDH1A1POLBMEN1KMT2APSMD14 | |
| SCHEMBL3604145 | 0.92 | ALDH1A1 (0.86) | ALDH1A1POLBMEN1KMT2APSMD14 | |
| SCHEMBL3604143 | 0.92 | ALDH1A1 (0.86) | ALDH1A1POLBMEN1KMT2APSMD14 | |
| SCHEMBL3606773 | 0.87 | ALDH1A1 (0.77) | ALDH1A1POLBMEN1KMT2APSMD14 | |
| SCHEMBL3606770 | 0.87 | ALDH1A1 (0.77) | ALDH1A1POLBMEN1KMT2APSMD14 | |
| SCHEMBL3614715 | 0.86 | ALDH1A1 (0.75) | ALDH1A1POLBMEN1KMT2APSMD14 | |
| SCHEMBL3614719 | 0.86 | ALDH1A1 (0.75) | ALDH1A1POLBMEN1KMT2APSMD14 | |
| SCHEMBL3599900 | 0.85 | ALDH1A1 (0.74) | ALDH1A1POLBMEN1KMT2APSMD14 | |
| SCHEMBL3605164 | 0.85 | ALDH1A1 (0.74) | ALDH1A1POLBMEN1KMT2APSMD14 | |
| SCHEMBL3616064 | 0.81 | ALDH1A1 (0.68) | ALDH1A1POLBMEN1KMT2APSMD14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100249165-A1 | PDZ DOMAIN MODULATORS | UNIVERSITY OF COPENHAGEN (DK) | 2010-09-30 | — | — | US | claimed |
| EP-2164478-A2 | PDZ DOMAIN MODULATORS | University of Copenhagen (DK) | 2010-03-24 | — | — | EP | claimed |
| WO-2008148747-A2 | PDZ DOMAIN MODULATORS | UNIVERSITY OF COPENHAGEN (DK) | 2008-12-11 | — | — | WO | claimed |
| US-20100249165-A1 | PDZ DOMAIN MODULATORS | UNIVERSITY OF COPENHAGEN (DK) | 2010-09-30 | — | — | US | disclosed |
| EP-2164478-A2 | PDZ DOMAIN MODULATORS | University of Copenhagen (DK) | 2010-03-24 | — | — | EP | disclosed |
| WO-2008148747-A2 | PDZ DOMAIN MODULATORS | UNIVERSITY OF COPENHAGEN (DK) | 2008-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249165-A1 | PDZ DOMAIN MODULATORS | PDLIM5, PSD, PDCD6IP | ALDH1A1 3764/4885POLB 4582/4885MEN1 3762/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.