Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.77 |
| ▸ | POLB | P06746 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.74 |
| ▸ | MEN1 | O00255 | 5/20 | 0.74 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3606773 | 1.00 | ALDH1A1 (0.77) | ALDH1A1POLBKMT2AMEN1PSMD14 | |
| SCHEMBL3597213 | 0.87 | ALDH1A1 (1.00) | ALDH1A1POLBKMT2AMEN1PSMD14 | |
| SCHEMBL3597216 | 0.87 | ALDH1A1 (1.00) | ALDH1A1POLBKMT2AMEN1PSMD14 | |
| SCHEMBL3605164 | 0.85 | ALDH1A1 (0.74) | ALDH1A1POLBKMT2AMEN1PSMD14 | |
| SCHEMBL3599900 | 0.85 | ALDH1A1 (0.74) | ALDH1A1POLBKMT2AMEN1PSMD14 | |
| SCHEMBL3604145 | 0.85 | ALDH1A1 (0.86) | ALDH1A1POLBKMT2AMEN1PSMD14 | |
| SCHEMBL3604143 | 0.85 | ALDH1A1 (0.86) | ALDH1A1POLBKMT2AMEN1PSMD14 | |
| SCHEMBL363338 | 0.82 | ALDH1A1 (0.71) | ALDH1A1POLBKMT2AMEN1MAPT | |
| SCHEMBL363339 | 0.82 | ALDH1A1 (0.71) | ALDH1A1POLBKMT2AMEN1MAPT | |
| SCHEMBL3607452 | 0.81 | ALDH1A1 (0.68) | ALDH1A1POLBKMT2AMEN1PSMD14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100249165-A1 | PDZ DOMAIN MODULATORS | UNIVERSITY OF COPENHAGEN (DK) | 2010-09-30 | — | — | US | disclosed |
| EP-2164478-A2 | PDZ DOMAIN MODULATORS | University of Copenhagen (DK) | 2010-03-24 | — | — | EP | disclosed |
| WO-2008148747-A2 | PDZ DOMAIN MODULATORS | UNIVERSITY OF COPENHAGEN (DK) | 2008-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249165-A1 | PDZ DOMAIN MODULATORS | PDLIM5, PSD, PDCD6IP | ALDH1A1 3764/4885POLB 4582/4885KMT2A 2830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.