Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL3613035 | 0.94 | PTK2 (0.41) | MEN1ALDH1A1MAPTMAPK1KMT2A | |
| SCHEMBL1628531 | 0.84 | SPR (0.37) | MEN1ALDH1A1MAPTMAPK1KMT2A | |
| SCHEMBL27739316 | 0.78 | KDM4E (0.41) | MEN1ALDH1A1MAPK1KMT2AMAPK8 | |
| SCHEMBL31128918 | 0.78 | ADORA2B (0.40) | MEN1ALDH1A1MAPTKMT2APIM1 | |
| SCHEMBL27739264 | 0.74 | TSHR (0.45) | MEN1ALDH1A1MAPTMAPK1KMT2A | |
| SCHEMBL1476821 | 0.74 | CYP2A6 (0.47) | MEN1ALDH1A1MAPTMAPK1KMT2A | |
| Hydrochloric Acid SCHEMBL27610019 | 0.73 | CYP2A6 (0.46) | MEN1ALDH1A1MAPTMAPK1KMT2A | |
| SCHEMBL5796937 | 0.72 | GAA (0.33) | GAA | |
| SCHEMBL3615811 | 0.71 | RPS6KA5 (0.39) | MAPTCHEK1ROCK1 | |
| SCHEMBL30753169 | 0.71 | MAPK1 (0.44) | MEN1ALDH1A1MAPTMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117412966-A | Condensed pyridines for combating invertebrate pests | FMC公司 | 2024-01-16 | — | — | CN | claimed |
| CN-119591582-A | Imide-based proteolytic modulators and related methods of use | 阿尔维纳斯运营股份有限公司 | 2025-03-11 | — | — | CN | disclosed |
| WO-2024208315-A1 | AROMATIC HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 中国医药研究开发中心有限公司 | 2024-10-10 | — | — | WO | disclosed |
| CN-118580252-A | PROTAC compound, pharmaceutical composition containing same, and preparation method and application thereof | 百极弘烨(南通)医药科技有限公司 | 2024-09-03 | — | — | CN | disclosed |
| CN-117412966-A | Condensed pyridines for combating invertebrate pests | FMC公司 | 2024-01-16 | — | — | CN | disclosed |
| US-8273736-B2 | Thienopyridine and furopyridine kinase inhibitors | ABBOTT LABORATORIES (US) | 2012-09-25 | — | — | US | disclosed |
| US-20100069371-A1 | THIENOPYRIDINE AND FUROPYRIDINE KINASE INHIBITORS | ABBOTT LABORATORIES (US) | 2010-03-18 | — | — | US | disclosed |
| CN-101189243-A | Substituted heterocycles and their use as CHK1, PDK1 and PAK inhibitors | ASTRAZENECA AB (SE) | 2008-05-28 | — | — | CN | disclosed |
| CN-1856498-A | Thienopyridine and furopyridine kinase inhibitors | ABBOTT LAB (US) | 2006-11-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069371-A1 | THIENOPYRIDINE AND FUROPYRIDINE KINASE INHIBITORS | ABL1, ERBB2, LCK | MEN1 2197/4885ALDH1A1 1899/4885MAPT 2008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.